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Mammalian-target of rapamycin inhibition with temsirolimus in myelodysplastic syndromes (MDS) patients is associated with considerable toxicity: results of the temsirolimus pilot trial by the German MDS Study Group (D-MDS).
Wermke, Martin; Schuster, Claudia; Nolte, Florian; Al-Ali, Haifa-Kathrin; Kiewe, Philipp; Schönefeldt, Claudia; Jakob, Christiane; von Bonin, Malte; Hentschel, Leopold; Klut, Ina-Maria; Ehninger, Gerhard; Bornhäuser, Martin; Baretton, Gustavo; Germing, Ulrich; Herbst, Regina; Haase, Detelef; Hofmann, Wolf K; Platzbecker, Uwe.
Afiliação
  • Wermke M; Department of Internal Medicine I, University Hospital Carl Gustav Carus, Dresden, Germany.
  • Schuster C; Early Clinical Trial Unit, University Cancer Centre, Dresden, Germany.
  • Nolte F; German Cancer Consortium (DKTK), Dresden, Germany.
  • Al-Ali HK; Department of Internal Medicine I, University Hospital Carl Gustav Carus, Dresden, Germany.
  • Kiewe P; Department of Internal Medicine, St. Hedwig Hospital, Berlin, Germany.
  • Schönefeldt C; Medical Faculty Mannheim of the University of Heidelberg, Mannheim, Germany.
  • Jakob C; Department of Haematology and Oncology, University Hospital, Leipzig, Germany.
  • von Bonin M; Department of Oncology, MVZ Oskar-Helene-Heim, Berlin, Germany.
  • Hentschel L; Institute of Forensic Medicine, Medical Faculty Carl Gustav Carus, Technical University Dresden, Dresden, Germany.
  • Klut IM; Institute of Pathology, University Hospital Carl Gustav Carus, Dresden, Germany.
  • Ehninger G; Department of Internal Medicine I, University Hospital Carl Gustav Carus, Dresden, Germany.
  • Bornhäuser M; German Cancer Consortium (DKTK), Dresden, Germany.
  • Baretton G; German Cancer Research Centre (DKFZ), Heidelberg, Germany.
  • Germing U; Department of Internal Medicine I, University Hospital Carl Gustav Carus, Dresden, Germany.
  • Herbst R; Clinical Pharmacy, University Hospital Carl Gustav Carus, Dresden, Germany.
  • Haase D; Department of Internal Medicine I, University Hospital Carl Gustav Carus, Dresden, Germany.
  • Hofmann WK; Department of Internal Medicine I, University Hospital Carl Gustav Carus, Dresden, Germany.
  • Platzbecker U; Institute of Pathology, University Hospital Carl Gustav Carus, Dresden, Germany.
Br J Haematol ; 175(5): 917-924, 2016 Dec.
Article em En | MEDLINE | ID: mdl-27714772
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Síndromes Mielodisplásicas / Sirolimo / Serina-Treonina Quinases TOR Tipo de estudo: Clinical_trials / Risk_factors_studies Limite: Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Br J Haematol Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Alemanha
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Síndromes Mielodisplásicas / Sirolimo / Serina-Treonina Quinases TOR Tipo de estudo: Clinical_trials / Risk_factors_studies Limite: Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Br J Haematol Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Alemanha