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The DNA cytosine deaminase APOBEC3B promotes tamoxifen resistance in ER-positive breast cancer.
Law, Emily K; Sieuwerts, Anieta M; LaPara, Kelly; Leonard, Brandon; Starrett, Gabriel J; Molan, Amy M; Temiz, Nuri A; Vogel, Rachel Isaksson; Meijer-van Gelder, Marion E; Sweep, Fred C G J; Span, Paul N; Foekens, John A; Martens, John W M; Yee, Douglas; Harris, Reuben S.
Afiliação
  • Law EK; Howard Hughes Medical Institute, University of Minnesota, Minneapolis, MN 55455, USA.; Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA.; Institute for Molecular Virology, University of Minnesota, Minneapolis, MN 55455, USA.; Department of Biochemistry, Molecular Biology an
  • Sieuwerts AM; Department of Medical Oncology and Cancer Genomics Netherlands, Erasmus MC Cancer Institute, 3015 GE Rotterdam, Netherlands.
  • LaPara K; Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA.
  • Leonard B; Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA.; Institute for Molecular Virology, University of Minnesota, Minneapolis, MN 55455, USA.; Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, MN 55455, USA.
  • Starrett GJ; Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA.; Institute for Molecular Virology, University of Minnesota, Minneapolis, MN 55455, USA.; Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, MN 55455, USA.
  • Molan AM; Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA.; Institute for Molecular Virology, University of Minnesota, Minneapolis, MN 55455, USA.; Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, MN 55455, USA.
  • Temiz NA; Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA.; Institute for Molecular Virology, University of Minnesota, Minneapolis, MN 55455, USA.; Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, MN 55455, USA.
  • Vogel RI; Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA.; Division of Gynecologic Oncology, Department of Obstetrics, Gynecology and Women's Health, University of Minnesota, Minneapolis, MN 55455, USA.
  • Meijer-van Gelder ME; Department of Medical Oncology and Cancer Genomics Netherlands, Erasmus MC Cancer Institute, 3015 GE Rotterdam, Netherlands.
  • Sweep FC; Department of Laboratory Medicine, Radboud University Medical Center, Nijmegen, Netherlands.
  • Span PN; Department of Radiation Oncology, Radboud University Medical Center, Nijmegen, Netherlands.
  • Foekens JA; Department of Medical Oncology and Cancer Genomics Netherlands, Erasmus MC Cancer Institute, 3015 GE Rotterdam, Netherlands.
  • Martens JW; Department of Medical Oncology and Cancer Genomics Netherlands, Erasmus MC Cancer Institute, 3015 GE Rotterdam, Netherlands.
  • Yee D; Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA.
  • Harris RS; Howard Hughes Medical Institute, University of Minnesota, Minneapolis, MN 55455, USA.; Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA.; Institute for Molecular Virology, University of Minnesota, Minneapolis, MN 55455, USA.; Department of Biochemistry, Molecular Biology an
Sci Adv ; 2(10): e1601737, 2016 Oct.
Article em En | MEDLINE | ID: mdl-27730215

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tamoxifeno / Neoplasias da Mama / Antígenos de Histocompatibilidade Menor / Resistencia a Medicamentos Antineoplásicos / Citidina Desaminase Limite: Animals / Female / Humans Idioma: En Revista: Sci Adv Ano de publicação: 2016 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tamoxifeno / Neoplasias da Mama / Antígenos de Histocompatibilidade Menor / Resistencia a Medicamentos Antineoplásicos / Citidina Desaminase Limite: Animals / Female / Humans Idioma: En Revista: Sci Adv Ano de publicação: 2016 Tipo de documento: Article