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Synthesis and biological evaluation of C-ring truncated deguelin derivatives as heat shock protein 90 (HSP90) inhibitors.
Kim, Ho Shin; Hong, Mannkyu; Ann, Jihyae; Yoon, Suyoung; Nguyen, Cong-Truong; Lee, Su-Chan; Lee, Ho-Young; Suh, Young-Ger; Seo, Ji Hae; Choi, Hoon; Kim, Jun Yong; Kim, Kyu-Won; Kim, Joohwan; Kim, Young-Myeong; Park, So-Jung; Park, Hyun-Ju; Lee, Jeewoo.
Afiliação
  • Kim HS; Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea.
  • Hong M; Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea.
  • Ann J; Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea.
  • Yoon S; Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea.
  • Nguyen CT; Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea.
  • Lee SC; Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea.
  • Lee HY; Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea.
  • Suh YG; Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea.
  • Seo JH; SNU-Harvard NeuroVascular Protection Research Center, College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea.
  • Choi H; SNU-Harvard NeuroVascular Protection Research Center, College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea.
  • Kim JY; SNU-Harvard NeuroVascular Protection Research Center, College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea.
  • Kim KW; SNU-Harvard NeuroVascular Protection Research Center, College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea; Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, Seoul National University, Seoul 08826, Republ
  • Kim J; School of Medicine, Kangwon National University, Kangwon-do 24341, Republic of Korea.
  • Kim YM; School of Medicine, Kangwon National University, Kangwon-do 24341, Republic of Korea.
  • Park SJ; School of Pharmacy, Sungkyunkwan University, Suwon 16419, Republic of Korea.
  • Park HJ; School of Pharmacy, Sungkyunkwan University, Suwon 16419, Republic of Korea.
  • Lee J; Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea. Electronic address: jeewoo@snu.ac.kr.
Bioorg Med Chem ; 24(22): 6082-6093, 2016 11 15.
Article em En | MEDLINE | ID: mdl-27745993
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Rotenona / Proteínas de Choque Térmico HSP90 / Neovascularização Patológica / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Bioorg Med Chem Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Rotenona / Proteínas de Choque Térmico HSP90 / Neovascularização Patológica / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Bioorg Med Chem Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2016 Tipo de documento: Article