Long-term survival after acute myocardial infarction in patients with hypertrophic cardiomyopathy.
Clin Cardiol
; 40(1): 26-31, 2017 Jan.
Article
em En
| MEDLINE
| ID: mdl-27748528
ABSTRACT
BACKGROUND:
Hypertrophic cardiomyopathy (HCM) is associated with poor prognosis. It has been reported that there is no difference in in-hospital mortality after acute myocardial infarction (AMI) between patients with and without HCM. However, whether there is a difference in long-term survival after AMI between patients with and without HCM remains unclear.HYPOTHESIS:
Long-term survival after AMI is worse in patients with vs without HCM.METHODS:
The clinical profiles of 91 consecutive patients with HCM and AMI (HCM group) and 91 sex- and age-matched patients with AMI without HCM (non-HCM group) were analyzed. The study endpoint was all-cause mortality.RESULTS:
During a follow-up period of 4.9 ± 3.6 years, all-cause mortality occurred in 25 patients (27.5%) in the HCM group and 13 patients (14.3%) in the non-HCM group. The survival of the HCM group was inferior to that of the non-HCM group (log-rank P = 0.039). During the first year of follow-up, 3 deaths (3.3%) occurred in the HCM group and 7 deaths (7.7%) occurred in the non-HCM group (log-rank P = 0.177). Among patients who survived beyond the first year of follow-up (172 patients), the annual mortality rates were 6.3% (95% confidence interval 4.0%-9.3%) in the HCM group and 1.6% (95% confidence interval 0.6%-3.5%) in the non-HCM group (log-rank P = 0.001).CONCLUSIONS:
AMI patients with HCM exhibited worse long-term survival than did AMI patients without HCM.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Cardiomiopatia Hipertrófica
/
Infarto do Miocárdio
Tipo de estudo:
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Female
/
Humans
/
Male
/
Middle aged
País/Região como assunto:
Asia
Idioma:
En
Revista:
Clin Cardiol
Ano de publicação:
2017
Tipo de documento:
Article
País de afiliação:
China