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The isoflavone fraction from soybean presents mRNA maturation inhibition activity.
Kurata, Masashi; Murata, Yuki; Momma, Keiko; Fouad Ali Mursi, Intisar; Takahashi, Masakazu; Miyamae, Yusaku; Kambe, Taiho; Nagao, Masaya; Narita, Hiroshi; Shibuya, Yasuyuki; Masuda, Seiji.
Afiliação
  • Kurata M; a Division of Integrated Life Sciences, Graduate School of Biostudies , Kyoto University , Kyoto , Japan.
  • Murata Y; b Department of Oral and Maxillofacial Surgery , Graduate School of Medical Sciences, Nagoya City University , Nagoya , Japan.
  • Momma K; c Department of Food and Nutrition , Kyoto Women's University , Kyoto , Japan.
  • Fouad Ali Mursi I; d Department of Living and Welfare , Kyoto Women's University , Kyoto , Japan.
  • Takahashi M; a Division of Integrated Life Sciences, Graduate School of Biostudies , Kyoto University , Kyoto , Japan.
  • Miyamae Y; e Department of Bioscience , Fukui Prefectural University , Fukui , Japan.
  • Kambe T; a Division of Integrated Life Sciences, Graduate School of Biostudies , Kyoto University , Kyoto , Japan.
  • Nagao M; a Division of Integrated Life Sciences, Graduate School of Biostudies , Kyoto University , Kyoto , Japan.
  • Narita H; a Division of Integrated Life Sciences, Graduate School of Biostudies , Kyoto University , Kyoto , Japan.
  • Shibuya Y; c Department of Food and Nutrition , Kyoto Women's University , Kyoto , Japan.
  • Masuda S; b Department of Oral and Maxillofacial Surgery , Graduate School of Medical Sciences, Nagoya City University , Nagoya , Japan.
Biosci Biotechnol Biochem ; 81(3): 551-554, 2017 Mar.
Article em En | MEDLINE | ID: mdl-27776450
ABSTRACT
Recent findings indicate that mRNA splicing inhibitors can be potential anticancer candidates. We have previously established a screening system which monitors mRNA processing in order to identify mRNA processing inhibitors. Among a number of dietary resources, isoflavone fractions showed an inhibitory effect of mRNA processing. These findings demonstrate that a variety of dietary sources have an impact on mRNA biogenesis.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Glycine max / RNA Mensageiro / Avaliação Pré-Clínica de Medicamentos / Isoflavonas Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Biosci Biotechnol Biochem Assunto da revista: BIOQUIMICA / BIOTECNOLOGIA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Japão
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Glycine max / RNA Mensageiro / Avaliação Pré-Clínica de Medicamentos / Isoflavonas Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Biosci Biotechnol Biochem Assunto da revista: BIOQUIMICA / BIOTECNOLOGIA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Japão