Bushen Qiangji Granule () medicated serum inhibits osteogenic differentiation of fibroblasts in ankylosing spondylitis by inhibiting the BMP/Smads signal pathway in vitro.

Liu, Hong-Xiao; Jiang, Nan; Liang, Hui-Ying; Zhou, Ying-Yan; Feng, Xing-Hua; Feng, Xiao-Yan; Zhang, He-Qiu; Wu, Zhi-Kui; Jiang, Quan; Fu, Jiao; Ma, Xiao-Juan; Chen, Peng

Liu, Hong-Xiao; Jiang, Nan; Liang, Hui-Ying; Zhou, Ying-Yan; Feng, Xing-Hua; Feng, Xiao-Yan; Zhang, He-Qiu; Wu, Zhi-Kui; Jiang, Quan; Fu, Jiao; Ma, Xiao-Juan; Chen, Peng.

Afiliação

Liu HX; Department of Rheumatology, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, 100053, China. liuhongxiao_123@163.com.
Jiang N; Department of Rheumatology, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, 100053, China.
Liang HY; Department of Rheumatology, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, 100053, China.
Zhou YY; Department of Rheumatology, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, 100053, China.
Feng XH; Department of Rheumatology, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, 100053, China.
Feng XY; Department of Vaccine Engineering, Beijing Institute of Basic Medical Sciences, Beijing, 100850, China.
Zhang HQ; Department of Vaccine Engineering, Beijing Institute of Basic Medical Sciences, Beijing, 100850, China.
Wu ZK; Department of Rheumatology, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, 100053, China.
Jiang Q; Department of Rheumatology, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, 100053, China.
Fu J; Department of Rheumatology, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, 100053, China.
Ma XJ; Department of Rheumatology, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, 100053, China.
Chen P; Department of Rheumatology, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, 100053, China.

Chin J Integr Med ; 22(11): 817-822, 2016 Nov.

Article em En | MEDLINE | ID: mdl-27783321

Assuntos

Proteínas Morfogenéticas Ósseas/metabolismo; Diferenciação Celular/efeitos dos fármacos; Medicamentos de Ervas Chinesas/farmacologia; Fibroblastos/patologia; Osteogênese/efeitos dos fármacos; Soro/metabolismo; Proteínas Smad/metabolismo; Espondilite Anquilosante/patologia; Adulto; Subunidade alfa 1 de Fator de Ligação ao Core/genética; Subunidade alfa 1 de Fator de Ligação ao Core/metabolismo; Fibroblastos/efeitos dos fármacos; Fibroblastos/metabolismo; Humanos; Pessoa de Meia-Idade; Osteogênese/genética; Fosforilação/efeitos dos fármacos; RNA Mensageiro/genética; RNA Mensageiro/metabolismo; Transdução de Sinais/efeitos dos fármacos; Espondilite Anquilosante/genética; Adulto Jovem

Palavras-chave

Bushen Qiangji Granule medicated serum; ankylosing spondylitis; fifibroblasts; ossifification

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Base de dados: MEDLINE Assunto principal: Osteogênese / Espondilite Anquilosante / Medicamentos de Ervas Chinesas / Diferenciação Celular / Proteínas Morfogenéticas Ósseas / Soro / Proteínas Smad / Fibroblastos Limite: Adult / Humans / Middle aged Idioma: En Revista: Chin J Integr Med Assunto da revista: TERAPIAS COMPLEMENTARES Ano de publicação: 2016 Tipo de documento: Article País de afiliação: China

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