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Insights of a Lead Optimization Study and Biological Evaluation of Novel 4-Hydroxytamoxifen Analogs as Estrogen-Related Receptor γ (ERRγ) Inverse Agonists.
Kim, Jina; Woo, Seo Yeon; Im, Chun Young; Yoo, Eun Kyung; Lee, Seungmi; Kim, Hyo-Ji; Hwang, Hee-Jong; Cho, Joong-Heui; Lee, Won Seok; Yoon, Heeseok; Kim, Shinae; Kwon, Oh-Bin; Hwang, Hayoung; Kim, Kyung-Hee; Jeon, Jae-Han; Singh, Thoudam Debraj; Kim, Sang Wook; Hwang, Sung Yeoun; Choi, Hueng-Sik; Lee, In-Kyu; Kim, Seong Heon; Jeon, Yong Hyun; Chin, Jungwook; Cho, Sung Jin.
Afiliação
  • Kim J; New Drug Development Center, Daegu-Gyeongbuk Medical Innovation Foundation , Daegu 41061, Korea.
  • Woo SY; New Drug Development Center, Daegu-Gyeongbuk Medical Innovation Foundation , Daegu 41061, Korea.
  • Im CY; New Drug Development Center, Daegu-Gyeongbuk Medical Innovation Foundation , Daegu 41061, Korea.
  • Yoo EK; Leading-Edge Research Center for Drug Discovery and Development for Diabetes and Metabolic Disease, Kyungpook National University Hospital , Daegu 41404, Korea.
  • Lee S; Leading-Edge Research Center for Drug Discovery and Development for Diabetes and Metabolic Disease, Kyungpook National University Hospital , Daegu 41404, Korea.
  • Kim HJ; New Drug Development Center, Daegu-Gyeongbuk Medical Innovation Foundation , Daegu 41061, Korea.
  • Hwang HJ; New Drug Development Center, Daegu-Gyeongbuk Medical Innovation Foundation , Daegu 41061, Korea.
  • Cho JH; New Drug Development Center, Daegu-Gyeongbuk Medical Innovation Foundation , Daegu 41061, Korea.
  • Lee WS; New Drug Development Center, Daegu-Gyeongbuk Medical Innovation Foundation , Daegu 41061, Korea.
  • Yoon H; New Drug Development Center, Daegu-Gyeongbuk Medical Innovation Foundation , Daegu 41061, Korea.
  • Kim S; New Drug Development Center, Daegu-Gyeongbuk Medical Innovation Foundation , Daegu 41061, Korea.
  • Kwon OB; New Drug Development Center, Daegu-Gyeongbuk Medical Innovation Foundation , Daegu 41061, Korea.
  • Hwang H; New Drug Development Center, Daegu-Gyeongbuk Medical Innovation Foundation , Daegu 41061, Korea.
  • Kim KH; New Drug Development Center, Daegu-Gyeongbuk Medical Innovation Foundation , Daegu 41061, Korea.
  • Jeon JH; Leading-Edge Research Center for Drug Discovery and Development for Diabetes and Metabolic Disease, Kyungpook National University Hospital , Daegu 41404, Korea.
  • Singh TD; Department of Internal Medicine, School of Medicine, Kyungpook National University , Daegu 41944, Korea.
  • Kim SW; Department of Nuclear Medicine, School of Medicine, Kyungpook National University , Daegu 41944, Korea.
  • Hwang SY; Korea Bio-Medical Science Institute , Seoul 06106, Republic of Korea.
  • Choi HS; Korea Bio-Medical Science Institute , Seoul 06106, Republic of Korea.
  • Lee IK; National Creative Research Initiatives Center for Nuclear Receptor Signals and Hormone Research Center, School of Biological Sciences and Technology, Chonnam National University , Gwangju 61186, Republic of Korea.
  • Kim SH; Leading-Edge Research Center for Drug Discovery and Development for Diabetes and Metabolic Disease, Kyungpook National University Hospital , Daegu 41404, Korea.
  • Jeon YH; Department of Internal Medicine, School of Medicine, Kyungpook National University , Daegu 41944, Korea.
  • Chin J; New Drug Development Center, Daegu-Gyeongbuk Medical Innovation Foundation , Daegu 41061, Korea.
  • Cho SJ; Leading-Edge Research Center for Drug Discovery and Development for Diabetes and Metabolic Disease, Kyungpook National University Hospital , Daegu 41404, Korea.
J Med Chem ; 59(22): 10209-10227, 2016 11 23.
Article em En | MEDLINE | ID: mdl-27805390
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Base de dados: MEDLINE Assunto principal: Tamoxifeno / Receptores de Estrogênio Limite: Humans Idioma: En Revista: J Med Chem Assunto da revista: QUIMICA Ano de publicação: 2016 Tipo de documento: Article
Buscar no Google
Imprimir
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PubMed Links

Base de dados: MEDLINE Assunto principal: Tamoxifeno / Receptores de Estrogênio Limite: Humans Idioma: En Revista: J Med Chem Assunto da revista: QUIMICA Ano de publicação: 2016 Tipo de documento: Article