Serum prealbumin, retinol-binding protein, transferrin, and albumin levels in patients with large bowel cancer.
J Natl Cancer Inst
; 61(3): 687-91, 1978 Sep.
Article
em En
| MEDLINE
| ID: mdl-278845
ABSTRACT
In a study of the levels of serum prealbumin (PALB), retinol-binding protein (RBP), transferrin (TF), and albumin (ALB) in patients with large bowel cancer, critical values were established as (g/liter) PALB, 0.15; RBP, 40 X 10(-3); TF, 2.0; and ALB, 30. Values consistently below these were taken as a sign of malnutrition. The proteins in this system were interrelated and tended to show a similar pattern of change. Metastatic colon cancer caused a relatively small decline of ALB compared to the mean in tumor-free patients. PALB was the most sensitive indicator of nutrition, and its levels and rates of change had a prognostic significance. A rapid fall of PALB often occurred 2--3 months prior to the patients's death; this preterminal phase in ambulant patients was frequently heralded by a progressive rise in the level of C-reactive protein in the absence of any obvious infection.
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Base de dados:
MEDLINE
Assunto principal:
Neoplasias Retais
/
Pré-Albumina
/
Proteínas de Ligação ao Retinol
/
Albumina Sérica
/
Transferrina
/
Neoplasias do Colo
/
Proteínas de Neoplasias
Tipo de estudo:
Prognostic_studies
Limite:
Female
/
Humans
/
Male
Idioma:
En
Revista:
J Natl Cancer Inst
Ano de publicação:
1978
Tipo de documento:
Article