TNF&#945;-stimulated gene-6 (TSG6) activates macrophage phenotype transition to prevent inflammatory lung injury.

Mittal, Manish; Tiruppathi, Chinnaswamy; Nepal, Saroj; Zhao, You-Yang; Grzych, Dagmara; Soni, Dheeraj; Prockop, Darwin J; Malik, Asrar B

TNFα-stimulated gene-6 (TSG6) activates macrophage phenotype transition to prevent inflammatory lung injury.

Mittal, Manish; Tiruppathi, Chinnaswamy; Nepal, Saroj; Zhao, You-Yang; Grzych, Dagmara; Soni, Dheeraj; Prockop, Darwin J; Malik, Asrar B.

Afiliação

Mittal M; Department of Pharmacology and Center for Lung and Vascular Biology, University of Illinois College of Medicine, Chicago, IL 60612.
Tiruppathi C; Department of Pharmacology and Center for Lung and Vascular Biology, University of Illinois College of Medicine, Chicago, IL 60612.
Nepal S; Department of Pharmacology and Center for Lung and Vascular Biology, University of Illinois College of Medicine, Chicago, IL 60612.
Zhao YY; Department of Pharmacology and Center for Lung and Vascular Biology, University of Illinois College of Medicine, Chicago, IL 60612.
Grzych D; Department of Pharmacology and Center for Lung and Vascular Biology, University of Illinois College of Medicine, Chicago, IL 60612.
Soni D; Department of Pharmacology and Center for Lung and Vascular Biology, University of Illinois College of Medicine, Chicago, IL 60612.
Prockop DJ; Institute for Regenerative Medicine, Texas A&M University Health Science Center and College of Medicine, Bryan, TX 77807 abmalik@uic.edu Prockop@medicine.tamhsc.edu.
Malik AB; Department of Pharmacology and Center for Lung and Vascular Biology, University of Illinois College of Medicine, Chicago, IL 60612 abmalik@uic.edu Prockop@medicine.tamhsc.edu.

Proc Natl Acad Sci U S A ; 113(50): E8151-E8158, 2016 12 13.

Article em En | MEDLINE | ID: mdl-27911817

Assuntos

Moléculas de Adesão Celular/imunologia; Lesão Pulmonar/prevenção & controle; Macrófagos/imunologia; Animais; Moléculas de Adesão Celular/deficiência; Moléculas de Adesão Celular/genética; Reprogramação Celular/imunologia; Inflamação/prevenção & controle; Mediadores da Inflamação/imunologia; Lipopolissacarídeos/toxicidade; Pulmão/irrigação sanguínea; Pulmão/efeitos dos fármacos; Pulmão/imunologia; Ativação de Macrófagos; Macrófagos/metabolismo; Camundongos; Camundongos Endogâmicos BALB C; Camundongos Endogâmicos C57BL; Camundongos Knockout; Fator 88 de Diferenciação Mieloide/metabolismo; NF-kappa B/metabolismo; Fenótipo; Fator de Transcrição STAT1/metabolismo; Fator de Transcrição STAT3/metabolismo; Transdução de Sinais; Receptor 4 Toll-Like/metabolismo

Palavras-chave

acute lung injury; biological sciences; immunology; inflammation; medical sciences

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Moléculas de Adesão Celular / Lesão Pulmonar / Macrófagos Limite: Animals Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2016 Tipo de documento: Article

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