Maximizing the Impact of Physiologically Based Oral Absorption Modeling and Simulation.
J Pharm Sci
; 106(3): 734-737, 2017 03.
Article
em En
| MEDLINE
| ID: mdl-27915208
ABSTRACT
The challenge of bringing innovative medicines to patients in combination with intense competition within the pharmaceutical industry has induced companies to develop quality medicines more efficiently and cost-effectively. State-of-the-art approaches to advance drug development have never been so urgent. One such approach that has been gaining traction within the industry is the application of modeling and simulation. In this commentary, the benefits of physiologically based oral absorption modeling and simulation in drug development are highlighted and suggestions for maximizing its impact are provided.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Simulação por Computador
/
Preparações Farmacêuticas
/
Absorção Gastrointestinal
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Modelos Biológicos
Limite:
Humans
Idioma:
En
Revista:
J Pharm Sci
Ano de publicação:
2017
Tipo de documento:
Article