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Structural Basis for Inhibitor-Induced Aggregation of HIV Integrase.
Gupta, Kushol; Turkki, Vesa; Sherrill-Mix, Scott; Hwang, Young; Eilers, Grant; Taylor, Louis; McDanal, Charlene; Wang, Ping; Temelkoff, David; Nolte, Robert T; Velthuisen, Emile; Jeffrey, Jerry; Van Duyne, Gregory D; Bushman, Frederic D.
Afiliação
  • Gupta K; Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.
  • Turkki V; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.
  • Sherrill-Mix S; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.
  • Hwang Y; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.
  • Eilers G; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.
  • Taylor L; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.
  • McDanal C; HIV DPU, Infectious Disease Therapy Area Unit GlaxoSmithKline, Research Triangle Park, North Carolina, United States of America.
  • Wang P; HIV DPU, Infectious Disease Therapy Area Unit GlaxoSmithKline, Research Triangle Park, North Carolina, United States of America.
  • Temelkoff D; HIV DPU, Infectious Disease Therapy Area Unit GlaxoSmithKline, Research Triangle Park, North Carolina, United States of America.
  • Nolte RT; Protein Cellular and Structural Science, GlaxoSmithKline, Collegeville, Pennsylvania, United States of America.
  • Velthuisen E; HIV DPU, Infectious Disease Therapy Area Unit GlaxoSmithKline, Research Triangle Park, North Carolina, United States of America.
  • Jeffrey J; HIV DPU, Infectious Disease Therapy Area Unit GlaxoSmithKline, Research Triangle Park, North Carolina, United States of America.
  • Van Duyne GD; Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.
  • Bushman FD; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.
PLoS Biol ; 14(12): e1002584, 2016 Dec.
Article em En | MEDLINE | ID: mdl-27935939

Texto completo: 1 Base de dados: MEDLINE Assunto principal: HIV-1 / Inibidores de Integrase de HIV / Integrase de HIV Idioma: En Revista: PLoS Biol Assunto da revista: BIOLOGIA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Base de dados: MEDLINE Assunto principal: HIV-1 / Inibidores de Integrase de HIV / Integrase de HIV Idioma: En Revista: PLoS Biol Assunto da revista: BIOLOGIA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Estados Unidos