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Pharmacological characterization of N-[(2S)-5-(6-fluoro-3-pyridinyl)-2, 3-dihydro-1H-inden-2-yl]-2-propanesulfonamide: a novel, clinical AMPA receptor positive allosteric modulator.
Ward, Simon E; Beswick, Paul; Calcinaghi, Novella; Dawson, Lee A; Gartlon, Jane; Graziani, Francesca; Jones, Declan N C; Lacroix, Laurent; Selina Mok, M H; Oliosi, Beatrice; Pardoe, Joanne; Starr, Kathryn; Woolley, Marie L; Harries, Mark H.
Afiliação
  • Ward SE; University of Sussex, Brighton, UK.
  • Beswick P; Neurosciences Centre of Excellence for Drug Discovery, GlaxoSmithKline, Harlow, UK.
  • Calcinaghi N; University of Sussex, Brighton, UK.
  • Dawson LA; Neurosciences Centre of Excellence for Drug Discovery, GlaxoSmithKline Medicines Research Centre, Verona, Italy.
  • Gartlon J; Neurosciences Centre of Excellence for Drug Discovery, GlaxoSmithKline, Harlow, UK.
  • Graziani F; Neurosciences Centre of Excellence for Drug Discovery, GlaxoSmithKline, Harlow, UK.
  • Jones DN; Neurosciences Centre of Excellence for Drug Discovery, GlaxoSmithKline Medicines Research Centre, Verona, Italy.
  • Lacroix L; Neurosciences Centre of Excellence for Drug Discovery, GlaxoSmithKline, Harlow, UK.
  • Selina Mok MH; Neurosciences Centre of Excellence for Drug Discovery, GlaxoSmithKline, Harlow, UK.
  • Oliosi B; Health Sciences Research Center, Whiteland's College, University of Roehampton, London, UK.
  • Pardoe J; Neurosciences Centre of Excellence for Drug Discovery, GlaxoSmithKline, Harlow, UK.
  • Starr K; Neurosciences Centre of Excellence for Drug Discovery, GlaxoSmithKline Medicines Research Centre, Verona, Italy.
  • Woolley ML; Neurosciences Centre of Excellence for Drug Discovery, GlaxoSmithKline, Harlow, UK.
  • Harries MH; Neurosciences Centre of Excellence for Drug Discovery, GlaxoSmithKline, Harlow, UK.
Br J Pharmacol ; 174(5): 370-385, 2017 03.
Article em En | MEDLINE | ID: mdl-28009436

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sulfonamidas / Comportamento Animal / Receptores de AMPA / Nootrópicos / Indenos Limite: Animals / Humans / Male Idioma: En Revista: Br J Pharmacol Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Reino Unido

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sulfonamidas / Comportamento Animal / Receptores de AMPA / Nootrópicos / Indenos Limite: Animals / Humans / Male Idioma: En Revista: Br J Pharmacol Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Reino Unido