Benzene poisoning, clinical and blood abnormalities in two Brazilian female gas station attendants: two case reports.
BMC Res Notes
; 10(1): 52, 2017 Jan 18.
Article
em En
| MEDLINE
| ID: mdl-28100263
ABSTRACT
BACKGROUND:
Brazilian gas station workers are chronically exposed to benzene, toluene, xylene (BTX) during their working time. Describe below two cases of latin female gas station workers with benzene poisoning symptoms and miscarriage history. CASE PRESENTATION In both cases were identified complex chromosomal rearrangements (CCR) with fluorescence in situ hybridization, applied to whole chromosome paints by chromosomes 1, 2 and 4. The lower natural killer cell (NK) cells have also been observed in cases correspondents, especially the rare type of NK (NKbright) in their peripheral blood cells.CONCLUSIONS:
It is known that acquired chromosomal aberrations are positively correlated with cancer and reproductive risk. In concordance, lower NK cytotoxicity increases the risk for cancer, as well. Thus, this is the first study providing hints on a possible causative relation of lower NK cytotoxicity and increase rates of chromosomal rearrangements including CCRs.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Benzeno
/
Exposição Ocupacional
Tipo de estudo:
Prognostic_studies
Limite:
Adult
/
Female
/
Humans
País/Região como assunto:
America do sul
/
Brasil
Idioma:
En
Revista:
BMC Res Notes
Ano de publicação:
2017
Tipo de documento:
Article
País de afiliação:
Brasil