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First-in-human phase 1 study of margetuximab (MGAH22), an Fc-modified chimeric monoclonal antibody, in patients with HER2-positive advanced solid tumors.
Bang, Y J; Giaccone, G; Im, S A; Oh, D Y; Bauer, T M; Nordstrom, J L; Li, H; Chichili, G R; Moore, P A; Hong, S; Stewart, S J; Baughman, J E; Lechleider, R J; Burris, H A.
Afiliação
  • Bang YJ; Department of Internal Medicine, Cancer Research Institute, Seoul National University College of Medicine, Seoul, South Korea.
  • Giaccone G; Department of Medical Oncology, National Cancer Institute, Bethesda, MD, USA.
  • Im SA; Department of Internal Medicine, Cancer Research Institute, Seoul National University College of Medicine, Seoul, South Korea.
  • Oh DY; Department of Internal Medicine, Cancer Research Institute, Seoul National University College of Medicine, Seoul, South Korea.
  • Bauer TM; Department of Drug Development, Sarah Cannon Research Institute and Tennessee Oncology, Nashville, TN, USA.
  • Nordstrom JL; MacroGenics, Inc, Rockville, Maryland 20850, USA.
  • Li H; MacroGenics, Inc, Rockville, Maryland 20850, USA.
  • Chichili GR; MacroGenics, Inc, Rockville, Maryland 20850, USA.
  • Moore PA; MacroGenics, Inc, Rockville, Maryland 20850, USA.
  • Hong S; MacroGenics, Inc, Rockville, Maryland 20850, USA.
  • Stewart SJ; Departamento de Física, Facultad de Ciencias Exactas, UNLP, IFLP-CONICET C.C.No. 67, 1900 La Plata, Argentina.
  • Baughman JE; MacroGenics, Inc, South San Francisco, USA.
  • Lechleider RJ; MacroGenics, Inc, Rockville, Maryland 20850, USA.
  • Burris HA; Department of Drug Development, Sarah Cannon Research Institute and Tennessee Oncology, Nashville, TN, USA.
Ann Oncol ; 28(4): 855-861, 2017 04 01.
Article em En | MEDLINE | ID: mdl-28119295
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Anticorpos Monoclonais / Neoplasias / Antineoplásicos Tipo de estudo: Clinical_trials Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Ann Oncol Assunto da revista: NEOPLASIAS Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Coréia do Sul
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Anticorpos Monoclonais / Neoplasias / Antineoplásicos Tipo de estudo: Clinical_trials Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Ann Oncol Assunto da revista: NEOPLASIAS Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Coréia do Sul