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USP15 attenuates IGF-I signaling by antagonizing Nedd4-induced IRS-2 ubiquitination.
Fukushima, Toshiaki; Yoshihara, Hidehito; Furuta, Haruka; Hakuno, Fumihiko; Iemura, Shun-Ichiro; Natsume, Tohru; Nakatsu, Yusuke; Kamata, Hideaki; Asano, Tomoichiro; Komada, Masayuki; Takahashi, Shin-Ichiro.
Afiliação
  • Fukushima T; Department of Medical Science, Graduate School of Medicine, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima City, Hiroshima, 734-8553, Japan; Cell Biology Unit, Institute of Innovative Research, Tokyo Institute of Technology, 4259 Nagatsuta, Midori-ku, Yokohama, 226-8501, Japan.
  • Yoshihara H; Laboratory of Protein Metabolism, Tokyo Metropolitan Institute of Medical Science, 2-1-6 Kamikitazawa, Setagaya-ku, Tokyo, 156-8506, Japan.
  • Furuta H; Department of Animal Sciences, Graduate School of Agriculture and Life Sciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo, 113-8657, Japan.
  • Hakuno F; Department of Animal Sciences, Graduate School of Agriculture and Life Sciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo, 113-8657, Japan; Department of Applied Biological Chemistry, Graduate School of Agriculture and Life Sciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tok
  • Iemura SI; Molecular Profiling Research Center for Drug Discovery (molprof), National Institute of Advanced Industrial Science and Technology (AIST), 2-4-7 Aomi, Koto-ku, Tokyo, 135-0064, Japan.
  • Natsume T; Molecular Profiling Research Center for Drug Discovery (molprof), National Institute of Advanced Industrial Science and Technology (AIST), 2-4-7 Aomi, Koto-ku, Tokyo, 135-0064, Japan.
  • Nakatsu Y; Department of Medical Science, Graduate School of Medicine, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima City, Hiroshima, 734-8553, Japan.
  • Kamata H; Department of Medical Science, Graduate School of Medicine, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima City, Hiroshima, 734-8553, Japan.
  • Asano T; Department of Medical Science, Graduate School of Medicine, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima City, Hiroshima, 734-8553, Japan.
  • Komada M; Cell Biology Unit, Institute of Innovative Research, Tokyo Institute of Technology, 4259 Nagatsuta, Midori-ku, Yokohama, 226-8501, Japan.
  • Takahashi SI; Department of Animal Sciences, Graduate School of Agriculture and Life Sciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo, 113-8657, Japan; Department of Applied Biological Chemistry, Graduate School of Agriculture and Life Sciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tok
Biochem Biophys Res Commun ; 484(3): 522-528, 2017 03 11.
Article em En | MEDLINE | ID: mdl-28126338
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fator de Crescimento Insulin-Like I / Transdução de Sinais / Ubiquitina-Proteína Ligases / Ubiquitinação / Proteínas Substratos do Receptor de Insulina / Complexos Endossomais de Distribuição Requeridos para Transporte / Proteases Específicas de Ubiquitina Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Biochem Biophys Res Commun Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Japão
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fator de Crescimento Insulin-Like I / Transdução de Sinais / Ubiquitina-Proteína Ligases / Ubiquitinação / Proteínas Substratos do Receptor de Insulina / Complexos Endossomais de Distribuição Requeridos para Transporte / Proteases Específicas de Ubiquitina Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Biochem Biophys Res Commun Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Japão