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ADP-ribosylhydrolase activity of Chikungunya virus macrodomain is critical for virus replication and virulence.
McPherson, Robert Lyle; Abraham, Rachy; Sreekumar, Easwaran; Ong, Shao-En; Cheng, Shang-Jung; Baxter, Victoria K; Kistemaker, Hans A V; Filippov, Dmitri V; Griffin, Diane E; Leung, Anthony K L.
Afiliação
  • McPherson RL; Department of Biochemistry and Molecular Biology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205.
  • Abraham R; W. Harry Feinstone Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205.
  • Sreekumar E; W. Harry Feinstone Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205.
  • Ong SE; Department of Pharmacology, University of Washington, Seattle, WA 98195.
  • Cheng SJ; Department of Biochemistry and Molecular Biology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205.
  • Baxter VK; W. Harry Feinstone Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205.
  • Kistemaker HA; Department of Molecular and Comparative Pathobiology, School of Medicine, Johns Hopkins University, Baltimore, MD 21205.
  • Filippov DV; Department of Bio-organic Synthesis, Leiden University, Einsteinweg 55, 2333 CC Leiden, The Netherlands.
  • Griffin DE; Department of Bio-organic Synthesis, Leiden University, Einsteinweg 55, 2333 CC Leiden, The Netherlands.
  • Leung AK; W. Harry Feinstone Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205; anthony.leung@jhu.edu dgriffi6@jhmi.edu.
Proc Natl Acad Sci U S A ; 114(7): 1666-1671, 2017 02 14.
Article em En | MEDLINE | ID: mdl-28143925
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Adenosina Difosfato Ribose / Vírus Chikungunya / Proteínas não Estruturais Virais / N-Glicosil Hidrolases Limite: Animals Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Adenosina Difosfato Ribose / Vírus Chikungunya / Proteínas não Estruturais Virais / N-Glicosil Hidrolases Limite: Animals Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2017 Tipo de documento: Article