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Munc18b Increases Insulin Granule Fusion, Restoring Deficient Insulin Secretion in Type-2 Diabetes Human and Goto-Kakizaki Rat Islets with Improvement in Glucose Homeostasis.
Qin, Tairan; Liang, Tao; Zhu, Dan; Kang, Youhou; Xie, Li; Dolai, Subhankar; Sugita, Shuzo; Takahashi, Noriko; Ostenson, Claes-Goran; Banks, Kate; Gaisano, Herbert Y.
Afiliação
  • Qin T; Department of Medicine, University of Toronto, Toronto, ON M5S 1A8, Canada.
  • Liang T; Department of Medicine, University of Toronto, Toronto, ON M5S 1A8, Canada.
  • Zhu D; Department of Medicine, University of Toronto, Toronto, ON M5S 1A8, Canada.
  • Kang Y; Department of Medicine, University of Toronto, Toronto, ON M5S 1A8, Canada.
  • Xie L; Department of Medicine, University of Toronto, Toronto, ON M5S 1A8, Canada.
  • Dolai S; Department of Medicine, University of Toronto, Toronto, ON M5S 1A8, Canada.
  • Sugita S; Department of Physiology, University of Toronto, Toronto, ON M5S 1A8, Canada; Division of Fundamental Neurobiology, University Health Network, Toronto, ON M5T 2S8, Canada.
  • Takahashi N; Laboratory of Physiological Chemistry, Institute of Medicinal Chemistry, Hoshi University, Shinagawa, Tokyo 142-8501, Japan.
  • Ostenson CG; Department of Molecular Medicine and Surgery, Endocrinology and Diabetology Unit, Karolinska Institutet, Karolinska University Hospital, SE-171 76 Stockholm, Sweden.
  • Banks K; Department of Physiology, University of Toronto, Toronto, ON M5S 1A8, Canada; Division of Comparative Medicine, University of Toronto, Toronto, ON M5S 1A8, Canada.
  • Gaisano HY; Department of Medicine, University of Toronto, Toronto, ON M5S 1A8, Canada; Department of Physiology, University of Toronto, Toronto, ON M5S 1A8, Canada. Electronic address: herbert.gaisano@utoronto.ca.
EBioMedicine ; 16: 262-274, 2017 Feb.
Article em En | MEDLINE | ID: mdl-28163042
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ilhotas Pancreáticas / Diabetes Mellitus Tipo 2 / Proteínas Munc18 / Glucose / Homeostase / Insulina Limite: Aged / Animals / Female / Humans / Male / Middle aged Idioma: En Revista: EBioMedicine Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Canadá
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ilhotas Pancreáticas / Diabetes Mellitus Tipo 2 / Proteínas Munc18 / Glucose / Homeostase / Insulina Limite: Aged / Animals / Female / Humans / Male / Middle aged Idioma: En Revista: EBioMedicine Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Canadá