Clustered, Regularly Interspaced Short Palindromic Repeats (CRISPR)/Cas9-coupled Affinity Purification/Mass Spectrometry Analysis Revealed a Novel Role of Neurofibromin in mTOR Signaling.

Li, Xu; Gao, Min; Choi, Jong Min; Kim, Beom-Jun; Zhou, Mao-Tian; Chen, Zhen; Jain, Antrix N; Jung, Sung Yun; Yuan, Jingsong; Wang, Wenqi; Wang, Yi; Chen, Junjie

Li, Xu; Gao, Min; Choi, Jong Min; Kim, Beom-Jun; Zhou, Mao-Tian; Chen, Zhen; Jain, Antrix N; Jung, Sung Yun; Yuan, Jingsong; Wang, Wenqi; Wang, Yi; Chen, Junjie.

Afiliação

Li X; From the Department of Experimental Radiation Oncology, University of Texas M.D. Anderson Cancer Center, Houston, Texas 77030.
Gao M; From the Department of Experimental Radiation Oncology, University of Texas M.D. Anderson Cancer Center, Houston, Texas 77030.
Choi JM; âDepartment of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas 77030.
Kim BJ; âDepartment of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas 77030.
Zhou MT; From the Department of Experimental Radiation Oncology, University of Texas M.D. Anderson Cancer Center, Houston, Texas 77030.
Chen Z; From the Department of Experimental Radiation Oncology, University of Texas M.D. Anderson Cancer Center, Houston, Texas 77030.
Jain AN; âDepartment of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas 77030.
Jung SY; âDepartment of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas 77030.
Yuan J; **Department of Radiation Oncology, Center for Radiological Research, Columbia University, New York, New York 10032.
Wang W; Department of Developmental and Cell Biology, University of California at Irvine, Irvine, California 92697 jchen8@mdanderson.org yiw@bcm.edu wenqiw6@uci.edu.
Wang Y; âDepartment of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas 77030; jchen8@mdanderson.org yiw@bcm.edu wenqiw6@uci.edu.
Chen J; From the Department of Experimental Radiation Oncology, University of Texas M.D. Anderson Cancer Center, Houston, Texas 77030; jchen8@mdanderson.org yiw@bcm.edu wenqiw6@uci.edu.

Mol Cell Proteomics ; 16(4): 594-607, 2017 04.

Article em En | MEDLINE | ID: mdl-28174230

Assuntos

Proteínas de Transporte/metabolismo; Edição de Genes/métodos; Neoplasias/metabolismo; Neurofibromina 1/metabolismo; Proteômica/métodos; Serina-Treonina Quinases TOR/metabolismo; Sistemas CRISPR-Cas; Proteínas de Transporte/genética; Proliferação de Células; Sobrevivência Celular; Células HEK293; Células HeLa; Humanos; Peptídeos e Proteínas de Sinalização Intracelular; Espectrometria de Massas; Neoplasias/genética; Neurofibromina 1/genética; Mapas de Interação de Proteínas; Transdução de Sinais; Serina-Treonina Quinases TOR/genética

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas de Transporte / Neurofibromina 1 / Proteômica / Serina-Treonina Quinases TOR / Edição de Genes / Neoplasias Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Mol Cell Proteomics Assunto da revista: BIOLOGIA MOLECULAR / BIOQUIMICA Ano de publicação: 2017 Tipo de documento: Article

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