Aerobic training prior to myocardial infarction increases cardiac GLUT4 and partially preserves heart function in spontaneously hypertensive rats.
Appl Physiol Nutr Metab
; 42(3): 334-337, 2017 Mar.
Article
em En
| MEDLINE
| ID: mdl-28177731
ABSTRACT
We assessed cardiac function (echocardiographic) and glucose transporter 4 (GLUT4) expression (Western blot) in response to 10 weeks of aerobic training (treadmill) prior to acute myocardial infarction (AMI) by ligation of the left coronary artery in spontaneously hypertensive rats. Animals were allocated to sedentary+sham, sedentary+AMI, training+sham, and training+AMI. Aerobic training prior to AMI partially preserves heart function. AMI and/or aerobic training increased GLUT4 expression. However, those animals trained prior to AMI showed a greater increase in GLUT4 in cardiomyocytes.
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Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Condicionamento Físico Animal
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Transportador de Glucose Tipo 4
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Infarto do Miocárdio
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Miocárdio
Limite:
Animals
Idioma:
En
Revista:
Appl Physiol Nutr Metab
Assunto da revista:
CIENCIAS DA NUTRICAO
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FISIOLOGIA
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MEDICINA ESPORTIVA
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METABOLISMO
Ano de publicação:
2017
Tipo de documento:
Article
País de afiliação:
Brasil