Probing Skin for Metabolites and Topical Drugs with Hydrogel Micropatches.

Dutkiewicz, Ewelina P; Chiu, Hsien-Yi; Urban, Pawel L

Dutkiewicz, Ewelina P; Chiu, Hsien-Yi; Urban, Pawel L.

Afiliação

Dutkiewicz EP; Department of Applied Chemistry, National Chiao Tung University , 1001 University Road, Hsinchu, 300, Taiwan.
Chiu HY; Department of Dermatology, National Taiwan University Hospital Hsin-Chu Branch , 25 Jingguo Road, Hsinchu, 300, Taiwan.
Urban PL; Department of Applied Chemistry, National Chiao Tung University , 1001 University Road, Hsinchu, 300, Taiwan.

Anal Chem ; 89(5): 2664-2670, 2017 03 07.

Article em En | MEDLINE | ID: mdl-28192981

ABSTRACT

ABSTRACT

Sampling the skin surface is a convenient way to obtain biological specimens bearing clinically relevant information. Hydrogel micropatches enable noninvasive collection of skin excretion specimens, which can subsequently be subjected to rapid mass spectrometric analysis providing insights into the skin metabolome.

Assuntos

Hidrogéis/química; Espectrometria de Massas; Metaboloma; Preparações Farmacêuticas/análise; Pele/metabolismo; Administração Tópica; Animais; Humanos; Preparações Farmacêuticas/metabolismo

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pele / Espectrometria de Massas / Preparações Farmacêuticas / Hidrogéis / Metaboloma Limite: Animals / Humans Idioma: En Revista: Anal Chem Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Taiwan

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