ScreenPro FH - Screening Project for Familial Hypercholesterolemia in Central, Southern and Eastern Europe: Basic Epidemiology.
Vnitr Lek
; 63(1): 25-30, 2017.
Article
em En
| MEDLINE
| ID: mdl-28225288
ABSTRACT
INTRODUCTION:
Despite great recent progress, familial hypercholesterolemia (FH) is still underestimated, under-diagnosed and thus undertreated worldwide. We have very little information on exact prevalence of patients with FH in the Central, Eastern and Southern Europe (CESE) region. The aim of the study was to describe the epidemiological situation in the CESE region from data available.METHODS:
All local leaders of the ScreenPro FH project were asked to provide local data on (a) expert guess of FH prevalence (b) the medical facilities focused on FH already in place (c) the diagnostic criteria used (d) the number of patients already evidenced in local database and (e) the availability of therapeutic options (especially plasma apheresis).RESULTS:
With the guess prevalence of FH around 1 500, we estimate the overall population of 588â¯363 FH heterozygotes in the CESE region. Only 14â¯108 persons (2.4 %) were depicted in local databases; but the depiction rate varied between 0.1 % and 31.6 %. Only four out of 17 participating countries reported the the LDL apheresis availability.CONCLUSION:
Our data point to the large population of heterozygous FH patients in the CESE region but low diagnostic rate. However structures through the ScreenPro FH project are being created and we can hope that the results will appear soon.Key words diagnosis - epidemiology - familial hypercholesterolemia - screening.
Buscar no Google
Base de dados:
MEDLINE
Assunto principal:
Hiperlipoproteinemia Tipo II
Tipo de estudo:
Diagnostic_studies
/
Prevalence_studies
/
Prognostic_studies
/
Risk_factors_studies
/
Screening_studies
Limite:
Humans
País/Região como assunto:
Europa
Idioma:
En
Revista:
Vnitr Lek
Ano de publicação:
2017
Tipo de documento:
Article