In vitro efficacy of a novel potassium oxalate hydrogel for dentin hypersensitivity.
Eur J Oral Sci
; 125(2): 151-159, 2017 04.
Article
em En
| MEDLINE
| ID: mdl-28247537
ABSTRACT
A novel potassium oxalate-based hydrogel is proposed for treating dentin hypersensitivity and this study evaluates its in vitro performance as a remineralizing, desensitizing agent. Etched disks of human dentin were treated for 10 or 20 min using the test hydrogel, to mimic a professional application with dental mouth guards. Dentin disks were evaluated in terms of permeability indexes in a fluid-filled system, the surface morphology was assessed by scanning electron microscopy, and the structural properties were studied using X-ray diffraction analysis. The potassium oxalate hydrogel significantly reduced dentin permeability, in a time-dependent manner, and occluded most of the patent dentinal tubules via crystal precipitation, forming a remineralized layer. After hydrogel treatments, an acid solution (pH 4.2) was applied to the disks for 30 s, or 1, 2, or 5 min, in order to reproduce a plaque-like oral acidity, and further analysis showed a good resistance of the remineralized layer to the acid challenge. The potassium oxalate-based hydrogel showed a better performance over commercially available products and artificial saliva, appearing a promising candidate for the treatment of dentin hypersensitivity.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Hidrogel de Polietilenoglicol-Dimetacrilato
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Ácido Oxálico
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Sensibilidade da Dentina
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Dessensibilizantes Dentinários
Limite:
Humans
Idioma:
En
Revista:
Eur J Oral Sci
Assunto da revista:
ODONTOLOGIA
Ano de publicação:
2017
Tipo de documento:
Article
País de afiliação:
Itália