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Methylpyrrole inhibitors of BET bromodomains.
Hasvold, Lisa A; Sheppard, George S; Wang, Le; Fidanze, Steven D; Liu, Dachun; Pratt, John K; Mantei, Robert A; Wada, Carol K; Hubbard, Robbert; Shen, Yu; Lin, Xiaoyu; Huang, Xiaoli; Warder, Scott E; Wilcox, Denise; Li, Leiming; Buchanan, F Greg; Smithee, Lauren; Albert, Daniel H; Magoc, Terrance J; Park, Chang H; Petros, Andrew M; Panchal, Sanjay C; Sun, Chaohong; Kovar, Peter; Soni, Nirupama B; Elmore, Steven W; Kati, Warren M; McDaniel, Keith F.
Afiliação
  • Hasvold LA; AbbVie Inc., Oncology Discovery, 1 North Waukegan Rd., North Chicago, IL 60064, USA.
  • Sheppard GS; AbbVie Inc., Oncology Discovery, 1 North Waukegan Rd., North Chicago, IL 60064, USA. Electronic address: george.s.sheppard@abbvie.com.
  • Wang L; AbbVie Inc., Oncology Discovery, 1 North Waukegan Rd., North Chicago, IL 60064, USA.
  • Fidanze SD; AbbVie Inc., Oncology Discovery, 1 North Waukegan Rd., North Chicago, IL 60064, USA.
  • Liu D; AbbVie Inc., Oncology Discovery, 1 North Waukegan Rd., North Chicago, IL 60064, USA.
  • Pratt JK; AbbVie Inc., Oncology Discovery, 1 North Waukegan Rd., North Chicago, IL 60064, USA.
  • Mantei RA; AbbVie Inc., Oncology Discovery, 1 North Waukegan Rd., North Chicago, IL 60064, USA.
  • Wada CK; AbbVie Inc., Oncology Discovery, 1 North Waukegan Rd., North Chicago, IL 60064, USA.
  • Hubbard R; AbbVie Inc., Oncology Discovery, 1 North Waukegan Rd., North Chicago, IL 60064, USA.
  • Shen Y; AbbVie Inc., Oncology Discovery, 1 North Waukegan Rd., North Chicago, IL 60064, USA.
  • Lin X; AbbVie Inc., Oncology Discovery, 1 North Waukegan Rd., North Chicago, IL 60064, USA.
  • Huang X; AbbVie Inc., Oncology Discovery, 1 North Waukegan Rd., North Chicago, IL 60064, USA.
  • Warder SE; AbbVie Inc., Oncology Discovery, 1 North Waukegan Rd., North Chicago, IL 60064, USA.
  • Wilcox D; AbbVie Inc., Oncology Discovery, 1 North Waukegan Rd., North Chicago, IL 60064, USA.
  • Li L; AbbVie Inc., Oncology Discovery, 1 North Waukegan Rd., North Chicago, IL 60064, USA.
  • Buchanan FG; AbbVie Inc., Oncology Discovery, 1 North Waukegan Rd., North Chicago, IL 60064, USA.
  • Smithee L; AbbVie Inc., Oncology Discovery, 1 North Waukegan Rd., North Chicago, IL 60064, USA.
  • Albert DH; AbbVie Inc., Oncology Discovery, 1 North Waukegan Rd., North Chicago, IL 60064, USA.
  • Magoc TJ; AbbVie Inc., Oncology Discovery, 1 North Waukegan Rd., North Chicago, IL 60064, USA.
  • Park CH; AbbVie Inc., Oncology Discovery, 1 North Waukegan Rd., North Chicago, IL 60064, USA.
  • Petros AM; AbbVie Inc., Oncology Discovery, 1 North Waukegan Rd., North Chicago, IL 60064, USA.
  • Panchal SC; AbbVie Inc., Oncology Discovery, 1 North Waukegan Rd., North Chicago, IL 60064, USA.
  • Sun C; AbbVie Inc., Oncology Discovery, 1 North Waukegan Rd., North Chicago, IL 60064, USA.
  • Kovar P; AbbVie Inc., Oncology Discovery, 1 North Waukegan Rd., North Chicago, IL 60064, USA.
  • Soni NB; AbbVie Inc., Oncology Discovery, 1 North Waukegan Rd., North Chicago, IL 60064, USA.
  • Elmore SW; AbbVie Inc., Oncology Discovery, 1 North Waukegan Rd., North Chicago, IL 60064, USA.
  • Kati WM; AbbVie Inc., Oncology Discovery, 1 North Waukegan Rd., North Chicago, IL 60064, USA.
  • McDaniel KF; AbbVie Inc., Oncology Discovery, 1 North Waukegan Rd., North Chicago, IL 60064, USA.
Bioorg Med Chem Lett ; 27(10): 2225-2233, 2017 05 15.
Article em En | MEDLINE | ID: mdl-28268136
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pirróis / Fatores de Transcrição / Proteínas Nucleares / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Bioorg Med Chem Lett Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pirróis / Fatores de Transcrição / Proteínas Nucleares / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Bioorg Med Chem Lett Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Estados Unidos