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Nanocrystalline cellulose-fullerene: Novel conjugates.
Herreros-López, A; Carini, M; Da Ros, T; Carofiglio, T; Marega, C; La Parola, V; Rapozzi, V; Xodo, L E; Alshatwi, Ali A; Hadad, C; Prato, M.
Afiliação
  • Herreros-López A; Centre of Excellence for Nanostructured Materials (CENMAT), INSTM, Department of Chemical and Pharmaceutical Sciences, University of Trieste, P.le Europa 1, 34127, Trieste, Italy. Electronic address: ana.herreroslopez@gmail.com.
  • Carini M; Centre of Excellence for Nanostructured Materials (CENMAT), INSTM, Department of Chemical and Pharmaceutical Sciences, University of Trieste, P.le Europa 1, 34127, Trieste, Italy. Electronic address: marco_carini@yahoo.it.
  • Da Ros T; Centre of Excellence for Nanostructured Materials (CENMAT), INSTM, Department of Chemical and Pharmaceutical Sciences, University of Trieste, P.le Europa 1, 34127, Trieste, Italy. Electronic address: daros@units.it.
  • Carofiglio T; Department of Chemical Sciences, University of Padova, Via Marzolo 1, 35131 Padova, Italy. Electronic address: tommaso.carofiglio@unipd.it.
  • Marega C; Department of Chemical Sciences, University of Padova, Via Marzolo 1, 35131 Padova, Italy. Electronic address: carla.marega@unipd.it.
  • La Parola V; Institute for the Nanostructured Materials Studies ISMN-CNR, Via La Malfa 153, 90146 Palermo, Italy. Electronic address: laparola@pa.ismn.cnr.it.
  • Rapozzi V; Department of Medical and Biological Sciences,, University of Udine, P.le Kolbe 4, 33100 Udine, Italy. Electronic address: valentina.rapozzi@uniud.it.
  • Xodo LE; Department of Medical and Biological Sciences,, University of Udine, P.le Kolbe 4, 33100 Udine, Italy. Electronic address: luigi.xodo@uniud.it.
  • Alshatwi AA; Department of Food and Nutrition, College of Food and Agriculture Science, King Saud University, P. O. Box 2460 Riyadh 11451, Saudi Arabia. Electronic address: alshatwi@ksu.edu.sa.
  • Hadad C; Centre of Excellence for Nanostructured Materials (CENMAT), INSTM, Department of Chemical and Pharmaceutical Sciences, University of Trieste, P.le Europa 1, 34127, Trieste, Italy. Electronic address: chadad@units.it.
  • Prato M; Centre of Excellence for Nanostructured Materials (CENMAT), INSTM, Department of Chemical and Pharmaceutical Sciences, University of Trieste, P.le Europa 1, 34127, Trieste, Italy; CIC BiomaGUNE, Parque Tecnológico de San Sebastián, Paseo Miramón, 182, 20009 San Sebastián, Guipúzcoa, Spain; Basque Fo
Carbohydr Polym ; 164: 92-101, 2017 May 15.
Article em En | MEDLINE | ID: mdl-28325349
ABSTRACT
The covalent grafting of two amino-fullerene C60 derivatives (C60-LC-NH2 and C60-SC-NH2, LC=long chain and SC=short chain) onto the surface of TEMPO oxidized nanocrystalline cellulose (NCC-COOH) has been reported for the first time. These hybrids (NCC-LC-C60 and NCC-SC-C60) form stable colloidal suspensions at concentrations up to 0.5mg/mL and act as effective photosensitizers for singlet oxygen production as demonstrated by the oxidation of L-methionine-methyl ester to the corresponding sulphoxide. Using the same approach, in a one-pot reaction both a fluorescent target molecule (FITC-LC-NH2) and the C60-LC-NH2 derivative have been successfully attached covalently onto the NCC-COOH surface. These hybrids, which showed no cytotoxicity on MCF-7 human breast cancer cells could be good candidates in photodynamic cancer therapy.
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Revista: Carbohydr Polym Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Revista: Carbohydr Polym Ano de publicação: 2017 Tipo de documento: Article