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Inhibitors of protein arginine deiminases and their efficacy in animal models of multiple sclerosis.
Sarswat, Amit; Wasilewski, Ewa; Chakka, Sai K; Bello, Angelica M; Caprariello, Andrew V; Muthuramu, Chithra M; Stys, Peter K; Dunn, Shannon E; Kotra, Lakshmi P.
Afiliação
  • Sarswat A; Centre for Molecular Design and Preformulations, and Division of Experimental Therapeutics, Toronto General Research Institute, University Health Network, Toronto, Ontario M5G 1L7, Canada.
  • Wasilewski E; Centre for Molecular Design and Preformulations, and Division of Experimental Therapeutics, Toronto General Research Institute, University Health Network, Toronto, Ontario M5G 1L7, Canada; Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, Ontario M5S 3M2,
  • Chakka SK; Centre for Molecular Design and Preformulations, and Division of Experimental Therapeutics, Toronto General Research Institute, University Health Network, Toronto, Ontario M5G 1L7, Canada.
  • Bello AM; Centre for Molecular Design and Preformulations, and Division of Experimental Therapeutics, Toronto General Research Institute, University Health Network, Toronto, Ontario M5G 1L7, Canada; Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, Ontario M5S 3M2,
  • Caprariello AV; Hotchkiss Brain Institute and Department of Clinical Neurosciences, University of Calgary, Calgary, Alberta T2N 4N1, Canada.
  • Muthuramu CM; Centre for Molecular Design and Preformulations, and Division of Experimental Therapeutics, Toronto General Research Institute, University Health Network, Toronto, Ontario M5G 1L7, Canada.
  • Stys PK; Hotchkiss Brain Institute and Department of Clinical Neurosciences, University of Calgary, Calgary, Alberta T2N 4N1, Canada.
  • Dunn SE; Centre for Molecular Design and Preformulations, and Division of Experimental Therapeutics, Toronto General Research Institute, University Health Network, Toronto, Ontario M5G 1L7, Canada; Department of Immunology, University of Toronto, and Women's College Research Institute, Toronto, Ontario, M5S
  • Kotra LP; Centre for Molecular Design and Preformulations, and Division of Experimental Therapeutics, Toronto General Research Institute, University Health Network, Toronto, Ontario M5G 1L7, Canada; Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, Ontario M5S 3M2,
Bioorg Med Chem ; 25(9): 2643-2656, 2017 05 01.
Article em En | MEDLINE | ID: mdl-28341402
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tetrazóis / Inibidores Enzimáticos / Hidantoínas / Hidrolases / Imidazóis / Esclerose Múltipla Idioma: En Revista: Bioorg Med Chem Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Canadá
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tetrazóis / Inibidores Enzimáticos / Hidantoínas / Hidrolases / Imidazóis / Esclerose Múltipla Idioma: En Revista: Bioorg Med Chem Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Canadá