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Local delivery of novel MRTF/SRF inhibitors prevents scar tissue formation in a preclinical model of fibrosis.
Yu-Wai-Man, Cynthia; Spencer-Dene, Bradley; Lee, Richard M H; Hutchings, Kim; Lisabeth, Erika M; Treisman, Richard; Bailly, Maryse; Larsen, Scott D; Neubig, Richard R; Khaw, Peng T.
Afiliação
  • Yu-Wai-Man C; UCL Institute of Ophthalmology, London, UK. c.yu-wai-man@ucl.ac.uk.
  • Spencer-Dene B; National Institute for Health Research (NIHR) Biomedical Research Centre at Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London, UK. c.yu-wai-man@ucl.ac.uk.
  • Lee RMH; Signalling and Transcription Group, Francis Crick Institute, London, UK. c.yu-wai-man@ucl.ac.uk.
  • Hutchings K; Experimental Histopathology STP, Francis Crick Institute, London, UK.
  • Lisabeth EM; National Institute for Health Research (NIHR) Biomedical Research Centre at Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London, UK.
  • Treisman R; Vahlteich Medicinal Chemistry Core, College of Pharmacy, University of Michigan, Ann Arbor, MI, USA.
  • Bailly M; Department of Pharmacology and Toxicology, Michigan State University, East Lansing, MI, USA.
  • Larsen SD; Signalling and Transcription Group, Francis Crick Institute, London, UK.
  • Neubig RR; UCL Institute of Ophthalmology, London, UK.
  • Khaw PT; Vahlteich Medicinal Chemistry Core, College of Pharmacy, University of Michigan, Ann Arbor, MI, USA.
Sci Rep ; 7(1): 518, 2017 03 31.
Article em En | MEDLINE | ID: mdl-28364121
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transativadores / Cicatriz / Fator de Resposta Sérica Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: Sci Rep Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Reino Unido
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transativadores / Cicatriz / Fator de Resposta Sérica Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: Sci Rep Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Reino Unido