Development of certified reference materials for accurate determination of fluoroquinolone antibiotics in chicken meat.
Food Chem
; 229: 472-478, 2017 Aug 15.
Article
em En
| MEDLINE
| ID: mdl-28372203
ABSTRACT
Certified reference materials (CRMs; KRISS CRM 108-03-003, 108-03-004) were developed for the accurate determination of fluoroquinolones (enrofloxacin and ciprofloxacin, respectively) in chicken meat. Two groups of chickens were cured with feeds containing enrofloxacin and ciprofloxacin, respectively. After slaughter, the thigh and breast meats were combined for the respective groups and the meat was freeze-dried, pulverized, sieved, and V-mixed. The final bulk material was bottled in 10g portions. For certification of the CRMs, isotope dilution-liquid chromatography/tandem mass spectrometry was used. The certified values of the CRMs were (19.06±0.86)mg/kg for enrofloxacin and (1.095±0.038)mg/kg for ciprofloxacin. The stabilities of the CRMs were monitored at -70°C for 12months, at -20°C for 2months, and at room temperature for 1month. Both CRM candidates were stable during the monitoring period for each temperature.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Aves Domésticas
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Ciprofloxacina
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Fluoroquinolonas
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Análise de Alimentos
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Antibacterianos
Limite:
Animals
Idioma:
En
Revista:
Food Chem
Ano de publicação:
2017
Tipo de documento:
Article
País de afiliação:
Coréia do Sul