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Impact of air pollution on vitamin D deficiency and bone health in adolescents.
Feizabad, Elham; Hossein-Nezhad, Arash; Maghbooli, Zhila; Ramezani, Majid; Hashemian, Roxana; Moattari, Syamak.
Afiliação
  • Feizabad E; Department of Community Medicine, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
  • Hossein-Nezhad A; Department of Medicine, Section of Endocrinology, Nutrition and Diabetes, Boston University School of Medicine, 85 E Newton St, Boston, MA, 02118, USA. arash_hsi@yahoo.com.
  • Maghbooli Z; Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, 5th floor, Shariati Hospital, North Kargar, Tehran, 141142386, Iran. arash_hsi@yahoo.com.
  • Ramezani M; Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, 5th floor, Shariati Hospital, North Kargar, Tehran, 141142386, Iran.
  • Hashemian R; Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, 5th floor, Shariati Hospital, North Kargar, Tehran, 141142386, Iran.
  • Moattari S; Boston University School of Dental Medicine, 100 E Newton St, Boston, MA, 02118, USA.
Arch Osteoporos ; 12(1): 34, 2017 Dec.
Article em En | MEDLINE | ID: mdl-28378273
ABSTRACT
The association between air pollution and bone health was evaluated in adolescents in the city of Tehran. This study is essentially ecological. Vitamin D deficiency among adolescents has been reported at higher rates in polluted areas than in non-polluted areas. Additionally, residence in polluted areas is associated with lower levels of bone alkaline phosphatase.

PURPOSE:

The aim of this study was to evaluate the association between ambient air pollution and bone turnover in adolescents and to compare the prevalence of vitamin D deficiency between polluted and non-polluted areas of Tehran.

METHODS:

This cross-sectional population-based study was conducted on 325 middle- and high-school students (both girls and boys) in Tehran in the winter. During the study period, detailed daily data on air pollution were obtained from archived data collected by Tehran Air Quality Control Company (AQCC). Serum levels of calcium, phosphorus, parathyroid hormone (PTH), bone-specific alkaline phosphatase, 25(OH) vitamin D, osteocalcin, cross-linked C-telopeptide (CTX), total protein, albumin, and creatinine were obtained from the study group.

RESULTS:

Vitamin D deficiency was more prevalent in polluted areas than in non-polluted areas. After adjustment for age and sex, residence in the polluted area showed a statistically significant positive association with vitamin D deficiency and a statistically significant negative association with bone turnover. Interestingly, high calcium intake (>5000 mg/week) protects against the effects of air pollution on bone turnover.

CONCLUSIONS:

Air pollution is a chief factor determining the amount of solar UVB that reaches the earth's surface. Thus, atmospheric pollution may play a significant independent role in the development of vitamin D deficiency.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Deficiência de Vitamina D / Remodelação Óssea / Poluição do Ar Tipo de estudo: Observational_studies / Prevalence_studies / Risk_factors_studies Limite: Adolescent / Female / Humans / Male País/Região como assunto: Asia Idioma: En Revista: Arch Osteoporos Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Irã

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Deficiência de Vitamina D / Remodelação Óssea / Poluição do Ar Tipo de estudo: Observational_studies / Prevalence_studies / Risk_factors_studies Limite: Adolescent / Female / Humans / Male País/Região como assunto: Asia Idioma: En Revista: Arch Osteoporos Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Irã