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Dihydroxylated 2,6-diphenyl-4-chlorophenylpyridines: Topoisomerase I and IIα dual inhibitors with DNA non-intercalative catalytic activity.
Bist, Ganesh; Park, Seojeong; Song, Chanju; Thapa Magar, Til Bahadur; Shrestha, Aarajana; Kwon, Youngjoo; Lee, Eung-Seok.
Afiliação
  • Bist G; College of Pharmacy, Yeungnam University, Gyeongsan 712-749, Republic of Korea.
  • Park S; College of Pharmacy, Graduate School of Pharmaceutical Sciences, Ewha Global Top5 program, Ewha Womans University, Seoul 120-750, Republic of Korea.
  • Song C; College of Pharmacy, Graduate School of Pharmaceutical Sciences, Ewha Global Top5 program, Ewha Womans University, Seoul 120-750, Republic of Korea.
  • Thapa Magar TB; College of Pharmacy, Yeungnam University, Gyeongsan 712-749, Republic of Korea.
  • Shrestha A; College of Pharmacy, Yeungnam University, Gyeongsan 712-749, Republic of Korea.
  • Kwon Y; College of Pharmacy, Graduate School of Pharmaceutical Sciences, Ewha Global Top5 program, Ewha Womans University, Seoul 120-750, Republic of Korea. Electronic address: ykwon@ewha.ac.kr.
  • Lee ES; College of Pharmacy, Yeungnam University, Gyeongsan 712-749, Republic of Korea. Electronic address: eslee@yu.ac.kr.
Eur J Med Chem ; 133: 69-84, 2017 Jun 16.
Article em En | MEDLINE | ID: mdl-28384547
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Piridinas / DNA Topoisomerases Tipo I / Inibidores da Topoisomerase II Limite: Humans Idioma: En Revista: Eur J Med Chem Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Piridinas / DNA Topoisomerases Tipo I / Inibidores da Topoisomerase II Limite: Humans Idioma: En Revista: Eur J Med Chem Ano de publicação: 2017 Tipo de documento: Article