Contribution of the TP53 R337H mutation to the cancer burden in southern Brazil: Insights from the study of 55 families of children with adrenocortical tumors.

Mastellaro, Maria J; Seidinger, Ana L; Kang, Guolian; Abrahão, Renata; Miranda, Eliana C M; Pounds, Stanley B; Cardinalli, Izilda A; Aguiar, Simone S; Figueiredo, Bonald C; Rodriguez-Galindo, Carlos; Brandalise, Silvia R; Yunes, José A; Barros-Filho, Antônio de A; Ribeiro, Raul C

Mastellaro, Maria J; Seidinger, Ana L; Kang, Guolian; Abrahão, Renata; Miranda, Eliana C M; Pounds, Stanley B; Cardinalli, Izilda A; Aguiar, Simone S; Figueiredo, Bonald C; Rodriguez-Galindo, Carlos; Brandalise, Silvia R; Yunes, José A; Barros-Filho, Antônio de A; Ribeiro, Raul C.

Afiliação

Mastellaro MJ; Graduate Program in Child and Adolescent Health, School of Medical Sciences, University of Campinas, Campinas, Sao Paulo, Brazil.
Seidinger AL; Pediatric Oncology Department, Boldrini Children's Center, Campinas, Sao Paulo, Brazil.
Kang G; Medical Genetics Department, School of Medical Sciences, University of Campinas, Campinas, Sao Paulo, Brazil.
Abrahão R; Molecular Biology Laboratory, Boldrini Children's Center, Campinas, Campinas, Sao Paulo, Brazil.
Miranda ECM; Department of Biostatistics, St Jude Children's Research Hospital, Memphis, Tennessee.
Pounds SB; Department of Noncommunicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, United Kingdom.
Cardinalli IA; Data Center and Statistics, Hematology and Hemotherapy Department, University of Campinas, Campinas, Sao Paulo, Brazil.
Aguiar SS; Department of Biostatistics, St Jude Children's Research Hospital, Memphis, Tennessee.
Figueiredo BC; Department of Pathology, Boldrini Children's Center, Campinas, Sao Paulo, Brazil.
Rodriguez-Galindo C; Pediatric Oncology Department, Boldrini Children's Center, Campinas, Sao Paulo, Brazil.
Brandalise SR; Center for Pediatrics Research (CIPED), University of Campinas, Campinas, Sao Paulo, Brazil.
Yunes JA; Federal University of Parana and Pele Pequeno Principe Research Institute, Curitiba, Parana, Brazil.
Barros-Filho AA; Department of Global Medicine, International Outreach Program, St Jude Children's Research Hospital, Memphis, Tennessee.
Ribeiro RC; Department of Oncology, St Jude Children's Research Hospital, Memphis, Tennessee.

Cancer ; 123(16): 3150-3158, 2017 Aug 15.

Article em En | MEDLINE | ID: mdl-28387921

Assuntos

Neoplasias do Córtex Suprarrenal/genética; Neoplasias da Mama/genética; Neoplasias Gástricas/genética; Proteína Supressora de Tumor p53/genética; Adolescente; Adulto; Brasil; Criança; Pré-Escolar; Família; Feminino; Predisposição Genética para Doença; Heterozigoto; Humanos; Lactente; Masculino; Pessoa de Meia-Idade; Neoplasias/genética; Adulto Jovem

Palavras-chave

adrenocortical tumors; arginine-to-histidine mutation at codon 337 (R337H); childhood cancer; familial cancer; gastric cancer; tumor protein p53 (TP53)

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Gástricas / Neoplasias da Mama / Proteína Supressora de Tumor p53 / Neoplasias do Córtex Suprarrenal Tipo de estudo: Prognostic_studies Limite: Adolescent / Adult / Child / Child, preschool / Female / Humans / Infant / Male / Middle aged País/Região como assunto: America do sul / Brasil Idioma: En Revista: Cancer Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Brasil

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