Rifampicin reverses nicardipine effect inducing uncontrolled essential hypertension.

Cordeanu, Elena-Mihaela; Gaertner, Sébastien; Faller, Alix; Mirea, Corina; Lessinger, Jean-Marc; Kemmel, Veronique; Stephan, Dominique

Cordeanu, Elena-Mihaela; Gaertner, Sébastien; Faller, Alix; Mirea, Corina; Lessinger, Jean-Marc; Kemmel, Veronique; Stephan, Dominique.

Afiliação

Cordeanu EM; Department of Hypertension, Vascular Disease and Clinical Pharmacology, Strasbourg Regional University Hospital, Strasbourg, BP 426, 67091, France.
Gaertner S; Department of Hypertension, Vascular Disease and Clinical Pharmacology, Strasbourg Regional University Hospital, Strasbourg, BP 426, 67091, France.
Faller A; Department of Hypertension, Vascular Disease and Clinical Pharmacology, Strasbourg Regional University Hospital, Strasbourg, BP 426, 67091, France.
Mirea C; Department of Hypertension, Vascular Disease and Clinical Pharmacology, Strasbourg Regional University Hospital, Strasbourg, BP 426, 67091, France.
Lessinger JM; Department of Biochemistry and Molecular Biology, Strasbourg Regional University Hospital, Strasbourg, BP 426, 67091, France.
Kemmel V; Department of Biochemistry and Molecular Biology, Strasbourg Regional University Hospital, Strasbourg, BP 426, 67091, France.
Stephan D; Department of Hypertension, Vascular Disease and Clinical Pharmacology, Strasbourg Regional University Hospital, Strasbourg, BP 426, 67091, France.

Fundam Clin Pharmacol ; 31(5): 587-589, 2017 Oct.

Article em En | MEDLINE | ID: mdl-28407303

Assuntos

Hipertensão Essencial/induzido quimicamente; Hipertensão Essencial/diagnóstico; Nicardipino/efeitos adversos; Rifampina/uso terapêutico; Idoso; Antibióticos Antituberculose/sangue; Antibióticos Antituberculose/uso terapêutico; Anti-Hipertensivos/efeitos adversos; Anti-Hipertensivos/sangue; Bloqueadores dos Canais de Cálcio/efeitos adversos; Bloqueadores dos Canais de Cálcio/sangue; Interações Medicamentosas/fisiologia; Hipertensão Essencial/sangue; Feminino; Humanos; Nicardipino/sangue; Rifampina/sangue

Palavras-chave

CYP3A4; arterial hypertension; dihydropyridine; hepatic inducer; rifampicin

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Rifampina / Nicardipino / Hipertensão Essencial Limite: Aged / Female / Humans Idioma: En Revista: Fundam Clin Pharmacol Assunto da revista: FARMACOLOGIA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: França

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