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Decoupling stability and release in disulfide bonds with antibody-small molecule conjugates.
Pillow, Thomas H; Sadowsky, Jack D; Zhang, Donglu; Yu, Shang-Fan; Del Rosario, Geoffrey; Xu, Keyang; He, Jintang; Bhakta, Sunil; Ohri, Rachana; Kozak, Katherine R; Ha, Edward; Junutula, Jagath R; Flygare, John A.
Afiliação
  • Pillow TH; Research & Early Development , Genentech, Inc. , 1 DNA Way , South San Francisco , CA 94080 , USA . Email: thomashp@gene.com.
  • Sadowsky JD; Research & Early Development , Genentech, Inc. , 1 DNA Way , South San Francisco , CA 94080 , USA . Email: thomashp@gene.com.
  • Zhang D; Research & Early Development , Genentech, Inc. , 1 DNA Way , South San Francisco , CA 94080 , USA . Email: thomashp@gene.com.
  • Yu SF; Research & Early Development , Genentech, Inc. , 1 DNA Way , South San Francisco , CA 94080 , USA . Email: thomashp@gene.com.
  • Del Rosario G; Research & Early Development , Genentech, Inc. , 1 DNA Way , South San Francisco , CA 94080 , USA . Email: thomashp@gene.com.
  • Xu K; Research & Early Development , Genentech, Inc. , 1 DNA Way , South San Francisco , CA 94080 , USA . Email: thomashp@gene.com.
  • He J; Research & Early Development , Genentech, Inc. , 1 DNA Way , South San Francisco , CA 94080 , USA . Email: thomashp@gene.com.
  • Bhakta S; Research & Early Development , Genentech, Inc. , 1 DNA Way , South San Francisco , CA 94080 , USA . Email: thomashp@gene.com.
  • Ohri R; Research & Early Development , Genentech, Inc. , 1 DNA Way , South San Francisco , CA 94080 , USA . Email: thomashp@gene.com.
  • Kozak KR; Research & Early Development , Genentech, Inc. , 1 DNA Way , South San Francisco , CA 94080 , USA . Email: thomashp@gene.com.
  • Ha E; Research & Early Development , Genentech, Inc. , 1 DNA Way , South San Francisco , CA 94080 , USA . Email: thomashp@gene.com.
  • Junutula JR; Research & Early Development , Genentech, Inc. , 1 DNA Way , South San Francisco , CA 94080 , USA . Email: thomashp@gene.com.
  • Flygare JA; Research & Early Development , Genentech, Inc. , 1 DNA Way , South San Francisco , CA 94080 , USA . Email: thomashp@gene.com.
Chem Sci ; 8(1): 366-370, 2017 Jan 01.
Article em En | MEDLINE | ID: mdl-28451181
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Revista: Chem Sci Ano de publicação: 2017 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Idioma: En Revista: Chem Sci Ano de publicação: 2017 Tipo de documento: Article