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HMGA1 amplifies Wnt signalling and expands the intestinal stem cell compartment and Paneth cell niche.
Xian, Lingling; Georgess, Dan; Huso, Tait; Cope, Leslie; Belton, Amy; Chang, Yu-Ting; Kuang, Wenyong; Gu, Qihua; Zhang, Xiaoyan; Senger, Stefania; Fasano, Alessio; Huso, David L; Ewald, Andrew J; Resar, Linda M S.
Afiliação
  • Xian L; Division of Hematology, Department of Medicine, The Johns Hopkins University School of Medicine, 720 Rutland Avenue, Ross Research Building, Room 1025, Baltimore, Maryland 21205, USA.
  • Georgess D; Department of Cell Biology, The Johns Hopkins University School of Medicine, 855 North Wolfe Street, Baltimore, Maryland 21205, USA.
  • Huso T; Division of Hematology, Department of Medicine, The Johns Hopkins University School of Medicine, 720 Rutland Avenue, Ross Research Building, Room 1025, Baltimore, Maryland 21205, USA.
  • Cope L; Division of Biostatistics, Department of Oncology, The Johns Hopkins University School of Medicine, 550 North Broadway, Baltimore, Maryland 21205, USA.
  • Belton A; Division of Hematology, Department of Medicine, The Johns Hopkins University School of Medicine, 720 Rutland Avenue, Ross Research Building, Room 1025, Baltimore, Maryland 21205, USA.
  • Chang YT; Department of Pathology, Pathobiology Graduate Program, The Johns Hopkins University School of Medicine, 720 Rutland Avenue, Ross Research Building, Room 1025, Baltimore, Maryland 21205, USA.
  • Kuang W; Division of Hematology, Department of Medicine, The Johns Hopkins University School of Medicine, 720 Rutland Avenue, Ross Research Building, Room 1025, Baltimore, Maryland 21205, USA.
  • Gu Q; Division of Hematology, Department of Medicine, The Johns Hopkins University School of Medicine, 720 Rutland Avenue, Ross Research Building, Room 1025, Baltimore, Maryland 21205, USA.
  • Zhang X; Division of Hematology, Department of Medicine, The Johns Hopkins University School of Medicine, 720 Rutland Avenue, Ross Research Building, Room 1025, Baltimore, Maryland 21205, USA.
  • Senger S; Department of Pediatrics, Mucosal Immunology and Biology Research Center, Harvard Medical School, Massachusetts General Hospital East, 16th Street, Building 114, Charlestown, Massachusetts 02114, USA.
  • Fasano A; Department of Pediatrics, Mucosal Immunology and Biology Research Center, Harvard Medical School, Massachusetts General Hospital East, 16th Street, Building 114, Charlestown, Massachusetts 02114, USA.
  • Huso DL; Department of Molecular and Comparative Pathobiology, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA.
  • Ewald AJ; Department of Cell Biology, The Johns Hopkins University School of Medicine, 855 North Wolfe Street, Baltimore, Maryland 21205, USA.
  • Resar LMS; Department of Oncology, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA.
Nat Commun ; 8: 15008, 2017 04 28.
Article em En | MEDLINE | ID: mdl-28452345
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Células-Tronco / Celulas de Paneth / Proteína HMGA1a / Via de Sinalização Wnt / Mucosa Intestinal Limite: Animals / Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Células-Tronco / Celulas de Paneth / Proteína HMGA1a / Via de Sinalização Wnt / Mucosa Intestinal Limite: Animals / Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Estados Unidos