Central Venous-to-Arterial Carbon Dioxide Partial Pressure Difference in Patients Undergoing Cardiac Surgery is Not Related to Postoperative Outcomes.
J Cardiothorac Vasc Anesth
; 31(4): 1190-1196, 2017 Aug.
Article
em En
| MEDLINE
| ID: mdl-28457779
ABSTRACT
OBJECTIVE:
The objective of this study was to assess the association between increased central venous-to-arterial carbon dioxide difference (ΔPCO2) following cardiac surgery with cardiopulmonary bypass and postoperative morbidity and mortality.DESIGN:
A prospective, observational, non-interventional study. PATIENTS Three hundred ninety-three patients undergoing cardiac surgery with cardiopulmonary bypass.INTERVENTIONS:
The primary endpoint was the occurrence of one or more major postoperative complications. A ΔPCO2 ≥ 6 mmHg was considered to be abnormal. Data were first analyzed globally, and then according to 4 subgroups based on time course of ΔPCO2 during the study period [(1) persistently normal ΔPCO2; (2) increasing ΔPCO2; (3) decreasing ΔPCO2; and (4) persistently high ΔPCO2].RESULTS:
A total of 238 of the 393 (61%) patients developed complications. The major postoperative complication rate did not differ among the 4 groups 64% (n = 9) in group 1, 62% (n = 21) in group 2, 53% (n = 32) in group 3, and 62% (n = 176) in group 4 (p = 0.568). Mortality rates did not differ among the 4 groups (p > 0.05). ΔPCO2 was correlated weakly with perfusion parameters.CONCLUSIONS:
These results suggested that ΔPCO2 is not predictive of postoperative complications or mortality.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Complicações Pós-Operatórias
/
Dióxido de Carbono
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Pressão Venosa Central
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Procedimentos Cirúrgicos Cardíacos
Tipo de estudo:
Etiology_studies
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Observational_studies
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Prognostic_studies
Limite:
Aged
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Aged80
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
J Cardiothorac Vasc Anesth
Assunto da revista:
ANESTESIOLOGIA
/
CARDIOLOGIA
Ano de publicação:
2017
Tipo de documento:
Article