Neoadjuvant chemoradiotherapy with concurrent cisplatin/5-fluorouracil is associated with increased pathologic complete response and improved survival compared to carboplatin/paclitaxel in patients with locally advanced esophageal cancer.

Haisley, K R; Hart, K D; Nabavizadeh, N; Bensch, K G; Vaccaro, G M; Thomas, C R; Schipper, P H; Hunter, J G; Dolan, J P

Haisley, K R; Hart, K D; Nabavizadeh, N; Bensch, K G; Vaccaro, G M; Thomas, C R; Schipper, P H; Hunter, J G; Dolan, J P.

Afiliação

Haisley KR; Division of Gastrointestinal and General Surgery, Department of Surgery.
Hart KD; Division of Gastrointestinal and General Surgery, Department of Surgery.
Nabavizadeh N; Department of Radiation Medicine.
Bensch KG; Division of Medical Oncology, Department of Internal Medicine.
Vaccaro GM; Division of Medical Oncology, Department of Internal Medicine.
Thomas CR; Department of Radiation Medicine.
Schipper PH; Division of Cardiovascular and General Thoracic Surgery, Department of Surgery, Oregon Health and Science University, Portland, OR, USA.
Hunter JG; Division of Gastrointestinal and General Surgery, Department of Surgery.
Dolan JP; Division of Gastrointestinal and General Surgery, Department of Surgery.

Dis Esophagus ; 30(7): 1-7, 2017 Jul 01.

Article em En | MEDLINE | ID: mdl-28475724

Assuntos

Protocolos de Quimioterapia Combinada Antineoplásica/uso terapêutico; Quimiorradioterapia Adjuvante/métodos; Neoplasias Esofágicas/terapia; Terapia Neoadjuvante/métodos; Idoso; Carboplatina/administração & dosagem; Cisplatino/administração & dosagem; Intervalo Livre de Doença; Esofagectomia; Feminino; Fluoruracila/administração & dosagem; Humanos; Estimativa de Kaplan-Meier; Masculino; Pessoa de Meia-Idade; Paclitaxel/administração & dosagem; Modelos de Riscos Proporcionais; Estudos Retrospectivos; Taxa de Sobrevida; Resultado do Tratamento

Palavras-chave

carboplatin + paclitaxel; cisplatin + 5-fluorouracil; esophageal cancer; neoadjuvant chemotherapy; pathologic complete response

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Esofágicas / Protocolos de Quimioterapia Combinada Antineoplásica / Terapia Neoadjuvante / Quimiorradioterapia Adjuvante Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Dis Esophagus Assunto da revista: GASTROENTEROLOGIA Ano de publicação: 2017 Tipo de documento: Article

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