Effect of 1,25-(OH)2D3 on Proliferation of Fibroblast-Like Synoviocytes and Expressions of Pro-Inflammatory Cytokines through Regulating MicroRNA-22 in a Rat Model of Rheumatoid Arthritis.

Fan, Ping; He, Lan; Hu, Nan; Luo, Jing; Zhang, Jing; Mo, Ling-Fei; Wang, Yan-Hua; Pu, Dan; Lv, Xiao-Hong; Hao, Zhi-Ming; Ding, Chang-Hai; Xue, Wu-Jun; Li, Yang

Fan, Ping; He, Lan; Hu, Nan; Luo, Jing; Zhang, Jing; Mo, Ling-Fei; Wang, Yan-Hua; Pu, Dan; Lv, Xiao-Hong; Hao, Zhi-Ming; Ding, Chang-Hai; Xue, Wu-Jun; Li, Yang.

Afiliação

Fan P; Department of Rheumatism and Immunology, Xi'an, China.
He L; Department of Renal Transplantation, Center of Nephrology, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Hu N; Department of Rheumatism and Immunology, Xi'an, China.
Luo J; Department of Rheumatism and Immunology, Xi'an, China.
Zhang J; Department of Rheumatism and Immunology, Xi'an, China.
Mo LF; Department of Rheumatism and Immunology, Xi'an, China.
Wang YH; Department of Rheumatism and Immunology, Xi'an, China.
Pu D; Department of Rheumatism and Immunology, Xi'an, China.
Lv XH; Department of Rheumatism and Immunology, Xi'an, China.
Hao ZM; Department of Rheumatism and Immunology, Xi'an, China.
Ding CH; Department of Rheumatism and Immunology, Xi'an, China.
Xue WJ; University of Tasmania, Tasmania, Tasmania, Australia.
Li Y; Department of Renal Transplantation, Center of Nephrology, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.

Cell Physiol Biochem ; 42(1): 145-155, 2017.

Article em En | MEDLINE | ID: mdl-28528333

Assuntos

Artrite Reumatoide/patologia; Colecalciferol/farmacologia; Citocinas/análise; MicroRNAs/metabolismo; Animais; Antagomirs/metabolismo; Apoptose; Artrite Reumatoide/genética; Artrite Reumatoide/metabolismo; Proliferação de Células; Células Cultivadas; Ciclo-Oxigenase 2/genética; Ciclo-Oxigenase 2/metabolismo; Citocinas/metabolismo; Dinoprostona/metabolismo; Modelos Animais de Doenças; Regulação para Baixo; Fibroblastos/citologia; Fibroblastos/efeitos dos fármacos; Fibroblastos/metabolismo; Masculino; Metaloproteinase 3 da Matriz/genética; Metaloproteinase 3 da Matriz/metabolismo; MicroRNAs/antagonistas & inibidores; MicroRNAs/genética; Óxido Nítrico Sintase Tipo II/genética; Óxido Nítrico Sintase Tipo II/metabolismo; Ratos; Ratos Sprague-Dawley; Sinoviócitos/citologia; Sinoviócitos/patologia

Palavras-chave

1,25-dihydroxyvitamin D3; Collagen induced arthritis; Fibroblast-like synoviocytes; MicroRNA-22; Pro-inflammatory cytokine; Rheumatoid arthritis

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Artrite Reumatoide / Citocinas / Colecalciferol / MicroRNAs Limite: Animals Idioma: En Revista: Cell Physiol Biochem Assunto da revista: BIOQUIMICA / FARMACOLOGIA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: China

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