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Wnt5a promotes Frizzled-4 signalosome assembly by stabilizing cysteine-rich domain dimerization.
DeBruine, Zachary J; Ke, Jiyuan; Harikumar, Kaleeckal G; Gu, Xin; Borowsky, Peter; Williams, Bart O; Xu, Wenqing; Miller, Laurence J; Xu, H Eric; Melcher, Karsten.
Afiliação
  • DeBruine ZJ; Center for Cancer and Cell Biology, Laboratory for Structural Biology and Biochemistry, Van Andel Research Institute, Grand Rapids, Michigan 49503, USA.
  • Ke J; Center for Cancer and Cell Biology, Laboratory of Structural Sciences, Van Andel Research Institute, Grand Rapids, Michigan 49503, USA.
  • Harikumar KG; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Scottsdale, Arizona 85259, USA.
  • Gu X; Center for Cancer and Cell Biology, Laboratory for Structural Biology and Biochemistry, Van Andel Research Institute, Grand Rapids, Michigan 49503, USA.
  • Borowsky P; Center for Cancer and Cell Biology, Laboratory for Structural Biology and Biochemistry, Van Andel Research Institute, Grand Rapids, Michigan 49503, USA.
  • Williams BO; Center for Skeletal Disease Research, Laboratory of Cell Signaling and Carcinogenesis, Van Andel Research Institute, Grand Rapids, Michigan 49503, USA.
  • Xu W; Department of Biological Structure, University of Washington, Seattle, Washington 98195, USA.
  • Miller LJ; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Scottsdale, Arizona 85259, USA.
  • Xu HE; Center for Cancer and Cell Biology, Laboratory of Structural Sciences, Van Andel Research Institute, Grand Rapids, Michigan 49503, USA.
  • Melcher K; Van Andel Research Institute/Shanghai Institute of Materia Medica Center, Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
Genes Dev ; 31(9): 916-926, 2017 05 01.
Article em En | MEDLINE | ID: mdl-28546512
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ácidos Graxos Monoinsaturados / Cisteína / Receptores Frizzled / Proteína Wnt-5a Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Genes Dev Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Estados Unidos
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ácidos Graxos Monoinsaturados / Cisteína / Receptores Frizzled / Proteína Wnt-5a Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Genes Dev Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Estados Unidos