Hsc70 chaperone activity is required for the cytosolic slow axonal transport of synapsin.

Ganguly, Archan; Han, Xuemei; Das, Utpal; Wang, Lina; Loi, Jonathan; Sun, Jichao; Gitler, Daniel; Caillol, Ghislaine; Leterrier, Christophe; Yates, John R; Roy, Subhojit

Ganguly, Archan; Han, Xuemei; Das, Utpal; Wang, Lina; Loi, Jonathan; Sun, Jichao; Gitler, Daniel; Caillol, Ghislaine; Leterrier, Christophe; Yates, John R; Roy, Subhojit.

Afiliação

Ganguly A; Department of Pathology, University of California, San Diego, La Jolla, CA.
Han X; Department of Cell Biology, The Scripps Research Institute, La Jolla, CA.
Das U; Department of Pathology, University of California, San Diego, La Jolla, CA.
Wang L; Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, WI.
Loi J; Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, WI.
Sun J; Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, WI.
Gitler D; Department of Physiology and Cell Biology, Faculty of Health Sciences, Ben-Gurion University of the Negev and Zlotowski Center for Neuroscience, Beer-Sheva, Israel.
Caillol G; Aix Marseille Université, Centre National de la Recherche Scientifique, NICN UMR7259, Marseille, France.
Leterrier C; Aix Marseille Université, Centre National de la Recherche Scientifique, NICN UMR7259, Marseille, France.
Yates JR; Department of Cell Biology, The Scripps Research Institute, La Jolla, CA.
Roy S; Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, WI roy27@wisc.edu.

J Cell Biol ; 216(7): 2059-2074, 2017 07 03.

Article em En | MEDLINE | ID: mdl-28559423

Assuntos

Transporte Axonal; Proteínas de Choque Térmico HSC70/metabolismo; Hipocampo/metabolismo; Neurônios/metabolismo; Sinapsinas/metabolismo; Animais; Feminino; Células HEK293; Proteínas de Choque Térmico HSC70/genética; Hipocampo/citologia; Humanos; Imunoprecipitação; Cinética; Masculino; Espectrometria de Massas; Camundongos Knockout; Microscopia/métodos; Modelos Biológicos; Complexos Multiproteicos; Mapas de Interação de Proteínas; Proteômica/métodos; Ratos; Sinapsinas/deficiência; Sinapsinas/genética; Transfecção

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transporte Axonal / Sinapsinas / Proteínas de Choque Térmico HSC70 / Hipocampo / Neurônios Limite: Animals / Female / Humans / Male Idioma: En Revista: J Cell Biol Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Canadá

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