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Susceptibility of Colistin-Resistant, Gram-Negative Bacteria to Antimicrobial Peptides and Ceragenins.
Hashemi, Marjan M; Rovig, John; Weber, Scott; Hilton, Brian; Forouzan, Mehdi M; Savage, Paul B.
Afiliação
  • Hashemi MM; Department of Chemistry and Biochemistry, Brigham Young University, Provo, Utah, USA.
  • Rovig J; Department of Chemistry and Biochemistry, Brigham Young University, Provo, Utah, USA.
  • Weber S; Department of Chemistry and Biochemistry, Brigham Young University, Provo, Utah, USA.
  • Hilton B; Department of Chemistry and Biochemistry, Brigham Young University, Provo, Utah, USA.
  • Forouzan MM; Department of Chemical Engineering, Brigham Young University, Provo, Utah, USA.
  • Savage PB; Department of Chemistry and Biochemistry, Brigham Young University, Provo, Utah, USA pbs@byu.edu.
Antimicrob Agents Chemother ; 61(8)2017 08.
Article em En | MEDLINE | ID: mdl-28584137
The susceptibility of colistin-resistant clinical isolates of Klebsiella pneumoniae to ceragenins and antimicrobial peptides (AMPs) suggests that there is little to no cross-resistance between colistin and ceragenins/AMPs and that lipid A modifications are found in bacteria with modest changes in susceptibility to ceragenins and with high levels of resistance to colistin. These results suggest that there are differences in the resistance mechanisms to colistin and ceragenins/AMPs.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pseudomonas aeruginosa / Esteroides / Colistina / Peptídeos Catiônicos Antimicrobianos / Acinetobacter baumannii / Klebsiella pneumoniae / Antibacterianos Limite: Humans Idioma: En Revista: Antimicrob Agents Chemother Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pseudomonas aeruginosa / Esteroides / Colistina / Peptídeos Catiônicos Antimicrobianos / Acinetobacter baumannii / Klebsiella pneumoniae / Antibacterianos Limite: Humans Idioma: En Revista: Antimicrob Agents Chemother Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Estados Unidos