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Development of Protein Degradation Inducers of Androgen Receptor by Conjugation of Androgen Receptor Ligands and Inhibitor of Apoptosis Protein Ligands.
Shibata, Norihito; Nagai, Katsunori; Morita, Yoko; Ujikawa, Osamu; Ohoka, Nobumichi; Hattori, Takayuki; Koyama, Ryokichi; Sano, Osamu; Imaeda, Yasuhiro; Nara, Hiroshi; Cho, Nobuo; Naito, Mikihiko.
Afiliação
  • Shibata N; Divisions of Molecular Target and Gene Therapy Products, National Institute of Health Sciences , 1-18-1 Kamiyoga, Setagaya-ku, Tokyo 158-8501, Japan.
  • Nagai K; Pharmaceutical Research Division, Takeda Pharmaceutical Co. Ltd. , 26-1, Muraoka-Higashi 2-chome, Fujisawa, Kanagawa 251-0012, Japan.
  • Morita Y; Pharmaceutical Research Division, Takeda Pharmaceutical Co. Ltd. , 26-1, Muraoka-Higashi 2-chome, Fujisawa, Kanagawa 251-0012, Japan.
  • Ujikawa O; Pharmaceutical Research Division, Takeda Pharmaceutical Co. Ltd. , 26-1, Muraoka-Higashi 2-chome, Fujisawa, Kanagawa 251-0012, Japan.
  • Ohoka N; Divisions of Molecular Target and Gene Therapy Products, National Institute of Health Sciences , 1-18-1 Kamiyoga, Setagaya-ku, Tokyo 158-8501, Japan.
  • Hattori T; Divisions of Molecular Target and Gene Therapy Products, National Institute of Health Sciences , 1-18-1 Kamiyoga, Setagaya-ku, Tokyo 158-8501, Japan.
  • Koyama R; Pharmaceutical Research Division, Takeda Pharmaceutical Co. Ltd. , 26-1, Muraoka-Higashi 2-chome, Fujisawa, Kanagawa 251-0012, Japan.
  • Sano O; Pharmaceutical Research Division, Takeda Pharmaceutical Co. Ltd. , 26-1, Muraoka-Higashi 2-chome, Fujisawa, Kanagawa 251-0012, Japan.
  • Imaeda Y; Pharmaceutical Research Division, Takeda Pharmaceutical Co. Ltd. , 26-1, Muraoka-Higashi 2-chome, Fujisawa, Kanagawa 251-0012, Japan.
  • Nara H; Pharmaceutical Research Division, Takeda Pharmaceutical Co. Ltd. , 26-1, Muraoka-Higashi 2-chome, Fujisawa, Kanagawa 251-0012, Japan.
  • Cho N; Pharmaceutical Research Division, Takeda Pharmaceutical Co. Ltd. , 26-1, Muraoka-Higashi 2-chome, Fujisawa, Kanagawa 251-0012, Japan.
  • Naito M; Divisions of Molecular Target and Gene Therapy Products, National Institute of Health Sciences , 1-18-1 Kamiyoga, Setagaya-ku, Tokyo 158-8501, Japan.
J Med Chem ; 61(2): 543-575, 2018 01 25.
Article em En | MEDLINE | ID: mdl-28594553
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Próstata / Receptores Androgênicos / Proteínas Inibidoras de Apoptose / Proteólise / Antineoplásicos Limite: Humans / Male Idioma: En Revista: J Med Chem Assunto da revista: QUIMICA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Japão
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Próstata / Receptores Androgênicos / Proteínas Inibidoras de Apoptose / Proteólise / Antineoplásicos Limite: Humans / Male Idioma: En Revista: J Med Chem Assunto da revista: QUIMICA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Japão