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4S-Hydroxylation of Insulin at ProB28 Accelerates Hexamer Dissociation and Delays Fibrillation.
Lieblich, Seth A; Fang, Katharine Y; Cahn, Jackson K B; Rawson, Jeffrey; LeBon, Jeanne; Ku, H Teresa; Tirrell, David A.
Afiliação
  • Lieblich SA; Division of Chemistry and Chemical Engineering, California Institute of Technology , Pasadena, California 91125, United States.
  • Fang KY; Division of Chemistry and Chemical Engineering, California Institute of Technology , Pasadena, California 91125, United States.
  • Cahn JKB; Division of Chemistry and Chemical Engineering, California Institute of Technology , Pasadena, California 91125, United States.
  • Rawson J; Department of Translational Research and Cellular Therapeutics, Diabetes and Metabolism Research Institute, City of Hope , Duarte, California 91010, United States.
  • LeBon J; Beckman Research Institute of City of Hope , Duarte, California 91010, United States.
  • Ku HT; Department of Translational Research and Cellular Therapeutics, Diabetes and Metabolism Research Institute, City of Hope , Duarte, California 91010, United States.
  • Tirrell DA; Department of Translational Research and Cellular Therapeutics, Diabetes and Metabolism Research Institute, City of Hope , Duarte, California 91010, United States.
J Am Chem Soc ; 139(25): 8384-8387, 2017 06 28.
Article em En | MEDLINE | ID: mdl-28598606
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Hidroxiprolina / Insulina Idioma: En Revista: J Am Chem Soc Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Hidroxiprolina / Insulina Idioma: En Revista: J Am Chem Soc Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Estados Unidos