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Evaluation of Small-Animal PET Outcome Measures to Detect Disease Modification Induced by BACE Inhibition in a Transgenic Mouse Model of Alzheimer Disease.
Deleye, Steven; Waldron, Ann-Marie; Verhaeghe, Jeroen; Bottelbergs, Astrid; Wyffels, Leonie; Van Broeck, Bianca; Langlois, Xavier; Schmidt, Mark; Stroobants, Sigrid; Staelens, Steven.
Afiliação
  • Deleye S; Molecular Imaging Center Antwerp, University of Antwerp, Antwerp, Belgium.
  • Waldron AM; Molecular Imaging Center Antwerp, University of Antwerp, Antwerp, Belgium.
  • Verhaeghe J; Molecular Imaging Center Antwerp, University of Antwerp, Antwerp, Belgium.
  • Bottelbergs A; Neuroscience Department, Janssen Pharmaceutica NV, Beerse, Belgium.
  • Wyffels L; Molecular Imaging Center Antwerp, University of Antwerp, Antwerp, Belgium.
  • Van Broeck B; Nuclear Medicine Department, University Hospital Antwerp, Antwerp, Belgium; and.
  • Langlois X; Neuroscience Department, Janssen Pharmaceutica NV, Beerse, Belgium.
  • Schmidt M; Foundational Neuroscience Center, Abbvie, Cambridge, Massachusetts.
  • Stroobants S; Neuroscience Department, Janssen Pharmaceutica NV, Beerse, Belgium.
  • Staelens S; Nuclear Medicine Department, University Hospital Antwerp, Antwerp, Belgium; and.
J Nucl Med ; 58(12): 1977-1983, 2017 12.
Article em En | MEDLINE | ID: mdl-28611242

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ácido Aspártico Endopeptidases / Secretases da Proteína Precursora do Amiloide / Doença de Alzheimer Limite: Animals / Humans Idioma: En Revista: J Nucl Med Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Bélgica

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ácido Aspártico Endopeptidases / Secretases da Proteína Precursora do Amiloide / Doença de Alzheimer Limite: Animals / Humans Idioma: En Revista: J Nucl Med Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Bélgica