Neuroleptic bioequivalency: tablet versus concentrate.
J Clin Pharmacol
; 25(4): 305-6, 1985.
Article
em En
| MEDLINE
| ID: mdl-2861214
ABSTRACT
Two forms of the antipsychotic neuroleptic molindone were administered to newly admitted psychotic patients. A coated tablet was administered for ten days, followed by administration of liquid concentrate in equivalent doses for four days. Plasma was analyzed by gas chromatography with electron capture for the parent compound following each dosing phase. Our data suggest that oral doses of the tablet and concentrate forms of this neuroleptic are equivalent in clinical bioavailability.
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Base de dados:
MEDLINE
Assunto principal:
Antipsicóticos
/
Indóis
/
Molindona
Limite:
Humans
Idioma:
En
Revista:
J Clin Pharmacol
Ano de publicação:
1985
Tipo de documento:
Article