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Small-Molecule Inhibitors of the Programmed Cell Death-1/Programmed Death-Ligand 1 (PD-1/PD-L1) Interaction via Transiently Induced Protein States and Dimerization of PD-L1.
Guzik, Katarzyna; Zak, Krzysztof M; Grudnik, Przemyslaw; Magiera, Katarzyna; Musielak, Bogdan; Törner, Ricarda; Skalniak, Lukasz; Dömling, Alexander; Dubin, Grzegorz; Holak, Tad A.
Afiliação
  • Guzik K; Department of Organic Chemistry, Faculty of Chemistry, Jagiellonian University , Ingardena 3, 30-060 Krakow, Poland.
  • Zak KM; Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University , Gronostajowa 7, 30-387 Krakow, Poland.
  • Grudnik P; Malopolska Centre of Biotechnology, Jagiellonian University , Gronostajowa 7a, 30-387 Krakow, Poland.
  • Magiera K; Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University , Gronostajowa 7, 30-387 Krakow, Poland.
  • Musielak B; Malopolska Centre of Biotechnology, Jagiellonian University , Gronostajowa 7a, 30-387 Krakow, Poland.
  • Törner R; Department of Organic Chemistry, Faculty of Chemistry, Jagiellonian University , Ingardena 3, 30-060 Krakow, Poland.
  • Skalniak L; Malopolska Centre of Biotechnology, Jagiellonian University , Gronostajowa 7a, 30-387 Krakow, Poland.
  • Dömling A; Department of Organic Chemistry, Faculty of Chemistry, Jagiellonian University , Ingardena 3, 30-060 Krakow, Poland.
  • Dubin G; Department of Organic Chemistry, Faculty of Chemistry, Jagiellonian University , Ingardena 3, 30-060 Krakow, Poland.
  • Holak TA; Department of Organic Chemistry, Faculty of Chemistry, Jagiellonian University , Ingardena 3, 30-060 Krakow, Poland.
J Med Chem ; 60(13): 5857-5867, 2017 07 13.
Article em En | MEDLINE | ID: mdl-28613862
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Bibliotecas de Moléculas Pequenas / Multimerização Proteica / Antígeno B7-H1 / Receptor de Morte Celular Programada 1 / Mapas de Interação de Proteínas Limite: Humans Idioma: En Revista: J Med Chem Assunto da revista: QUIMICA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Polônia
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Bibliotecas de Moléculas Pequenas / Multimerização Proteica / Antígeno B7-H1 / Receptor de Morte Celular Programada 1 / Mapas de Interação de Proteínas Limite: Humans Idioma: En Revista: J Med Chem Assunto da revista: QUIMICA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Polônia