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Niche-mediated depletion of the normal hematopoietic stem cell reservoir by Flt3-ITD-induced myeloproliferation.
Mead, Adam J; Neo, Wen Hao; Barkas, Nikolaos; Matsuoka, Sahoko; Giustacchini, Alice; Facchini, Raffaella; Thongjuea, Supat; Jamieson, Lauren; Booth, Christopher A G; Fordham, Nicholas; Di Genua, Cristina; Atkinson, Deborah; Chowdhury, Onima; Repapi, Emmanouela; Gray, Nicki; Kharazi, Shabnam; Clark, Sally-Ann; Bouriez, Tiphaine; Woll, Petter; Suda, Toshio; Nerlov, Claus; Jacobsen, Sten Eirik W.
Afiliação
  • Mead AJ; Haematopoietic Stem Cell Biology Laboratory, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK adam.mead@imm.ox.ac.uk.
  • Neo WH; Medical Research Council Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.
  • Barkas N; Haematopoietic Stem Cell Biology Laboratory, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.
  • Matsuoka S; Haematopoietic Stem Cell Biology Laboratory, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.
  • Giustacchini A; Department of Safety Research on Blood and Biological Products, National Institute of Infectious Diseases, Tokyo, Japan.
  • Facchini R; Haematopoietic Stem Cell Biology Laboratory, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.
  • Thongjuea S; Medical Research Council Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.
  • Jamieson L; Haematopoietic Stem Cell Biology Laboratory, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.
  • Booth CAG; Haematopoietic Stem Cell Biology Laboratory, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.
  • Fordham N; Medical Research Council Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.
  • Di Genua C; Haematopoietic Stem Cell Biology Laboratory, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.
  • Atkinson D; Haematopoietic Stem Cell Biology Laboratory, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.
  • Chowdhury O; Haematopoietic Stem Cell Biology Laboratory, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.
  • Repapi E; Haematopoietic Stem Cell Biology Laboratory, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.
  • Gray N; Haematopoietic Stem Cell Biology Laboratory, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.
  • Kharazi S; Haematopoietic Stem Cell Biology Laboratory, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.
  • Clark SA; Computational Biology Research Group, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.
  • Bouriez T; Computational Biology Research Group, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.
  • Woll P; Department of Medicine Huddinge, Center for Hematology and Regenerative Medicine, Karolinska Institutet, Stockholm, Sweden.
  • Suda T; Haematopoietic Stem Cell Biology Laboratory, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.
  • Nerlov C; Haematopoietic Stem Cell Biology Laboratory, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.
  • Jacobsen SEW; Haematopoietic Stem Cell Biology Laboratory, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.
J Exp Med ; 214(7): 2005-2021, 2017 Jul 03.
Article em En | MEDLINE | ID: mdl-28637883
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Células-Tronco Hematopoéticas / Proliferação de Células / Tirosina Quinase 3 Semelhante a fms / Nicho de Células-Tronco / Mutação Limite: Animals Idioma: En Revista: J Exp Med Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Reino Unido
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Células-Tronco Hematopoéticas / Proliferação de Células / Tirosina Quinase 3 Semelhante a fms / Nicho de Células-Tronco / Mutação Limite: Animals Idioma: En Revista: J Exp Med Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Reino Unido