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Quasi-simultaneous acquisition of nine secondary ions with seven detectors on NanoSIMS50L: application to biological samples.
Guillermier, Christelle; Steinhauser, Matthew L; Lechene, Claude P.
Afiliação
  • Guillermier C; Division of Genetics, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
  • Steinhauser ML; National Resource for Imaging Mass Spectrometry (NRIMS), Cambridge, MA, USA.
  • Lechene CP; Division of Genetics, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Surf Interface Anal ; 46(Suppl 1): 150-153, 2014 Nov.
Article em En | MEDLINE | ID: mdl-28649151
We employed a method of electrostatic peak switching allowing for the quasi-simultaneous measurement of 16O, 18O, C2H, C2D,12C14N, 13C14N, 12C15N, P, and S with the NanoSIMS 50L instrument to derive ratios for D/H, 13C/12C, 18O/16O, and 15N/14N from biological samples. This approach involves two steps: (i) derivation of the D/H ratio from measurements of C2D and C2H and (ii) switching of the voltage on deflection plates located in front of two detectors. The method is reliable and easy to set up compared with the magnetic peak-switching mode usually used to perform this type of analysis.
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Revista: Surf Interface Anal Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Base de dados: MEDLINE Idioma: En Revista: Surf Interface Anal Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Estados Unidos