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Eriocalyxin B, a novel autophagy inducer, exerts anti-tumor activity through the suppression of Akt/mTOR/p70S6K signaling pathway in breast cancer.
Zhou, Xunian; Yue, Grace Gar-Lee; Chan, Andrew Man-Lok; Tsui, Stephen Kwok-Wing; Fung, Kwok-Pui; Sun, Handong; Pu, Jianxin; Lau, Clara Bik-San.
Afiliação
  • Zhou X; School of Biomedical Sciences, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China; Institute of Chinese Medicine, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China.
  • Yue GG; Institute of Chinese Medicine, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China; State Key Laboratory of Phytochemistry and Plant Resources in West China, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China.
  • Chan AM; School of Biomedical Sciences, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China.
  • Tsui SK; School of Biomedical Sciences, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China.
  • Fung KP; School of Biomedical Sciences, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China; Institute of Chinese Medicine, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China; State Key Laboratory of Phytochemistry and Plant Resources in West China, The
  • Sun H; State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, Yunnan, China.
  • Pu J; State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, Yunnan, China. Electronic address: pujianxin@mail.kib.ac.cn.
  • Lau CB; Institute of Chinese Medicine, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China; State Key Laboratory of Phytochemistry and Plant Resources in West China, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China. Electronic address: claralau@cuhk.e
Biochem Pharmacol ; 142: 58-70, 2017 10 15.
Article em En | MEDLINE | ID: mdl-28669564

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Autofagia / Neoplasias da Mama / Proteínas Quinases S6 Ribossômicas 70-kDa / Diterpenos / Proteínas Proto-Oncogênicas c-akt / Serina-Treonina Quinases TOR / Antineoplásicos Fitogênicos Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: Biochem Pharmacol Ano de publicação: 2017 Tipo de documento: Article País de afiliação: China

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Autofagia / Neoplasias da Mama / Proteínas Quinases S6 Ribossômicas 70-kDa / Diterpenos / Proteínas Proto-Oncogênicas c-akt / Serina-Treonina Quinases TOR / Antineoplásicos Fitogênicos Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: Biochem Pharmacol Ano de publicação: 2017 Tipo de documento: Article País de afiliação: China