Phenotypic and genomic comparison of Mycobacterium aurum and surrogate model species to Mycobacterium tuberculosis: implications for drug discovery.

Namouchi, Amine; Cimino, Mena; Favre-Rochex, Sandrine; Charles, Patricia; Gicquel, Brigitte

Namouchi, Amine; Cimino, Mena; Favre-Rochex, Sandrine; Charles, Patricia; Gicquel, Brigitte.

Afiliação

Namouchi A; Centre for Ecological and Evolutionary Synthesis, Department of Biosciences, University of Oslo, P.O. Box 1066, Blindern NO-0316, Oslo, Norway. amine.namouchi@gmail.com.
Cimino M; Unit of Mycobacterial genetics, Institut Pasteur, 25-28, rue du Docteur Roux, 75724, Paris, Cedex 15, France.
Favre-Rochex S; Unit of Mycobacterial genetics, Institut Pasteur, 25-28, rue du Docteur Roux, 75724, Paris, Cedex 15, France.
Charles P; Unit of Mycobacterial genetics, Institut Pasteur, 25-28, rue du Docteur Roux, 75724, Paris, Cedex 15, France.
Gicquel B; Unit of Mycobacterial genetics, Institut Pasteur, 25-28, rue du Docteur Roux, 75724, Paris, Cedex 15, France. brigitte.gicquel@pasteur.fr.

BMC Genomics ; 18(1): 530, 2017 07 13.

Article em En | MEDLINE | ID: mdl-28705154

Assuntos

Descoberta de Drogas; Genômica; Mycobacterium tuberculosis/efeitos dos fármacos; Mycobacterium tuberculosis/genética; Fenótipo; Farmacorresistência Bacteriana/genética; Anotação de Sequência Molecular; Mycobacterium tuberculosis/metabolismo; Especificidade da Espécie

Palavras-chave

Comparative genomics; Drug discovery; Drug resistance; Mycobacterium Aurum; Tuberculosis; Whole genome sequencing

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fenótipo / Genômica / Descoberta de Drogas / Mycobacterium tuberculosis Idioma: En Revista: BMC Genomics Assunto da revista: GENETICA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Noruega

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