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Cord blood NK cells engineered to express IL-15 and a CD19-targeted CAR show long-term persistence and potent antitumor activity.
Liu, E; Tong, Y; Dotti, G; Shaim, H; Savoldo, B; Mukherjee, M; Orange, J; Wan, X; Lu, X; Reynolds, A; Gagea, M; Banerjee, P; Cai, R; Bdaiwi, M H; Basar, R; Muftuoglu, M; Li, L; Marin, D; Wierda, W; Keating, M; Champlin, R; Shpall, E; Rezvani, K.
Afiliação
  • Liu E; Department of Stem Cell Transplantation and Cellular Therapy, MD Anderson Cancer Center, Houston, TX, USA.
  • Tong Y; Department of Stem Cell Transplantation and Cellular Therapy, MD Anderson Cancer Center, Houston, TX, USA.
  • Dotti G; Department of Microbiology and Immunology, University of North Carolina, Chapel Hill, NC, USA.
  • Shaim H; Department of Stem Cell Transplantation and Cellular Therapy, MD Anderson Cancer Center, Houston, TX, USA.
  • Savoldo B; Department of Microbiology and Immunology, University of North Carolina, Chapel Hill, NC, USA.
  • Mukherjee M; The Center for Human Immunobiology, Baylor College of Medicine, Houston, TX, USA.
  • Orange J; The Center for Human Immunobiology, Baylor College of Medicine, Houston, TX, USA.
  • Wan X; Department of Stem Cell Transplantation and Cellular Therapy, MD Anderson Cancer Center, Houston, TX, USA.
  • Lu X; Department of Hematopathology, MD Anderson Cancer Center, Houston, TX, USA.
  • Reynolds A; Department of Hematopathology, MD Anderson Cancer Center, Houston, TX, USA.
  • Gagea M; Department of Veterinary Medicine & Surgery, MD Anderson Cancer Center, Houston, TX, USA.
  • Banerjee P; Department of Stem Cell Transplantation and Cellular Therapy, MD Anderson Cancer Center, Houston, TX, USA.
  • Cai R; Department of Stem Cell Transplantation and Cellular Therapy, MD Anderson Cancer Center, Houston, TX, USA.
  • Bdaiwi MH; Department of Stem Cell Transplantation and Cellular Therapy, MD Anderson Cancer Center, Houston, TX, USA.
  • Basar R; Department of Stem Cell Transplantation and Cellular Therapy, MD Anderson Cancer Center, Houston, TX, USA.
  • Muftuoglu M; Department of Stem Cell Transplantation and Cellular Therapy, MD Anderson Cancer Center, Houston, TX, USA.
  • Li L; Department of Stem Cell Transplantation and Cellular Therapy, MD Anderson Cancer Center, Houston, TX, USA.
  • Marin D; Department of Stem Cell Transplantation and Cellular Therapy, MD Anderson Cancer Center, Houston, TX, USA.
  • Wierda W; Department of Leukemia, MD Anderson Cancer Center, Houston, TX, USA.
  • Keating M; Department of Leukemia, MD Anderson Cancer Center, Houston, TX, USA.
  • Champlin R; Department of Stem Cell Transplantation and Cellular Therapy, MD Anderson Cancer Center, Houston, TX, USA.
  • Shpall E; Department of Stem Cell Transplantation and Cellular Therapy, MD Anderson Cancer Center, Houston, TX, USA.
  • Rezvani K; Department of Stem Cell Transplantation and Cellular Therapy, MD Anderson Cancer Center, Houston, TX, USA.
Leukemia ; 32(2): 520-531, 2018 02.
Article em En | MEDLINE | ID: mdl-28725044

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Células Matadoras Naturais / Antígenos CD19 / Interleucina-15 / Sangue Fetal / Receptores de Antígenos Quiméricos Tipo de estudo: Prognostic_studies Limite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Leukemia Assunto da revista: HEMATOLOGIA / NEOPLASIAS Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Células Matadoras Naturais / Antígenos CD19 / Interleucina-15 / Sangue Fetal / Receptores de Antígenos Quiméricos Tipo de estudo: Prognostic_studies Limite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Leukemia Assunto da revista: HEMATOLOGIA / NEOPLASIAS Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos