Exosomes: A Rising Star in Falling Hearts.
Front Physiol
; 8: 494, 2017.
Article
em En
| MEDLINE
| ID: mdl-28751864
ABSTRACT
Although exosomes were previously recognized as a mechanism for discharging useless cellular components, growing evidence has elucidated their roles in conveying information between cells. They contribute to cell-cell communication by carrying nucleic acids, proteins and lipids that can, in turn, regulate behavior of the target cells. Recent research suggested that exosomes extensively participate in progression of diverse cardiovascular diseases (CVDs), such as myocardial infarction, cardiomyopathy, pulmonary arterial hypertension and others. Here, we summarize effects of exosome-derived molecules (mainly microRNAs and proteins) on cardiac function, to examine their potential applications as biomarkers or therapeutics in CVDs.
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Base de dados:
MEDLINE
Idioma:
En
Revista:
Front Physiol
Ano de publicação:
2017
Tipo de documento:
Article
País de afiliação:
China